Protein Alignment GDAP1 and GstE2

DIOPT Version :9

• Sequence 1: NP_061845.2
• Gene: GDAP1 / 54332
• HGNCID: 15968
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_611324.1
• Gene: GstE2 / 37107
• FlyBaseID: FBgn0063498
• Length: 221
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 51/273 - (18%)
• Similarity: 89/273 - (32%)
• Gaps: 94/273 - (34%)

Human    25 KLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICE 89
            ||:||....|...:..:|.:....|..|..::.|...:|.:..|::.|....||:|.....:|.:
  Fly     4 KLVLYGMDISPPVRACKLTLRALNLDYEYKEMDLLAGDHFKDAFLKKNPQHTVPLLEDNGALIWD 68

Human    90 ATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPA 154
            :..|:.||                                   :|.|.:...|:|...|
  Fly    69 SHAIVCYL-----------------------------------VDKYANSDELYPRDLV------ 92

Human   155 YATTRIRSQIGNT---ESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVL 216
                 :|:|:...   ::.:..::..|..:  .|..:|..|..|    :.|..:|.....||..|
  Fly    93 -----LRAQVDQRLFFDASILFMSLRNVSI--PYFLRQVSLVPK----EKVDNIKDAYGHLENFL 146

Human   217 DQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVT---------LHRLKFLGFARRNWGNGK 272
                             |..|:|.|...|:||:....|         |..||:
  Fly   147 -----------------GDNPYLTGSQLTIADLCCGATASSLAAVLDLDELKY------------ 182

Human   273 RPNLETYYERVLK 285
             |.:..::||:.|
  Fly   183 -PKVAAWFERLSK 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDAP1	NP_061845.2	GST_N_GDAP1	26..98	CDD:239350	17/71 (24%)
		GST_C_GDAP1	179..289	CDD:198336	24/116 (21%)
		Required for mitochondrial localization	320..358
GstE2	NP_611324.1	GstA	5..196	CDD:223698	50/272 (18%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	18/107 (17%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	27/137 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154571
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840