Protein Alignment GDAP1 and GstT3

DIOPT Version :10

• Sequence 1: NP_061845.2
• Gene: GDAP1 / 54332
• HGNCID: 15968
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_001162808.1
• Gene: GstT3 / 33047
• FlyBaseID: FBgn0031117
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 318
• Identity: 63/318 - (19%)
• Similarity: 104/318 - (32%)
• Gaps: 99/318 - (31%)

Human     9 RGSPPLRAEGKADAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEH-NEPWFMRLN 72
            |.|.|:|            .|:...|..|:.:.::.....:..|:..|:|...|| .|.:...:|
  Fly    40 RMSAPIR------------YYYDLMSQPSRALFIIFRLSNMPFEDCVVALRNGEHLTEDFKKEIN 92

Human    73 STGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRE---LLDSLPMD 134
            ....||.:......:.|:..|:.||.   ...:.|..:..|..:...||..:.|   :...|...
  Fly    93 RFQRVPCIHDNGYKLAESVAILRYLS---AKGKIPEHLYPKYFVDQSRVDEFLEWQHMSLRLTCA 154

Human   135 AYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDH 199
            .|.....|.|.||                 |.|.||.|
  Fly   155 MYFRTVWLEPLLT-----------------GRTPSEAK--------------------------- 175

Human   200 DNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFA 264
                 ::....::|:.||.|        ||...||:. :|.|.|.|:||:..|..:.:.:...:.
  Fly   176 -----IETFRMQMERNLDVV--------EEVWLEGKD-FLTGSSLTVADIFAACEIEQTRMADYD 226

Human   265 RRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGT 322
            .|.    |.|.:..:.:||  |::.|..                :.||.:...|:.||
  Fly   227 VRI----KYPKIRAWLKRV--RQSCNPY----------------YDVAHEFVYKISGT 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDAP1	NP_061845.2	GST_N_GDAP1	26..98	CDD:239350	15/72 (21%)
		GST_C_GDAP1	179..289	CDD:198336	21/109 (19%)
		Required for mitochondrial localization	320..358		2/3 (67%)
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	17/90 (19%)
		GST_C_Theta	135..259	CDD:198292	38/203 (19%)