DRSC/TRiP Functional Genomics Resources

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Protein Alignment GDAP1 and GstE9

DIOPT Version :9

Sequence 1:NP_061845.2 Gene:GDAP1 / 54332 HGNCID:15968 Length:358 Species:Homo sapiens
Sequence 2:NP_725784.1 Gene:GstE9 / 246581 FlyBaseID:FBgn0063491 Length:221 Species:Drosophila melanogaster


Alignment Length:294 Identity:60/294 - (20%)
Similarity:91/294 - (30%) Gaps:103/294 - (35%)


- Green bases have known domain annotations that are detailed below.


Human    25 KLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICE 89
            ||:||....|...:..:|.:....|:.|...|:|...||....|...|....||||......|.|
  Fly     3 KLVLYGVEASPPVRACKLTLDALGLQYEYRLVNLLAGEHKTKEFSLKNPQHTVPVLEDDGKFIWE 67

Human    90 ATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDS---LPMDAYTHGCILH-------- 143
            :..|..||.:.:.          |....||:....|.|:|.   ........|||.:        
  Fly    68 SHAICAYLVRRYA----------KSDDLYPKDYFKRALVDQRLHFESGVLFQGCIRNIAIPLFYK 122

Human   144 -----PELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVK 203
                 |...:|::..||                        |..||:|                 
  Fly   123 NITEVPRSQIDAIYEAY------------------------DFLEAFI----------------- 146

Human   204 YLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNW 268
                                          |.|.:|||...|:||.|:..::..|  :|.|..  
  Fly   147 ------------------------------GNQAYLCGPVITIADYSVVSSVSSL--VGLAAI-- 177

Human   269 GNGKR-PNLETYYERVLKRKTFNKVLGHVNNILI 301
             :.|| |.|..:.:|:..:..:..:.|:...:||
  Fly   178 -DAKRYPKLNGWLDRMAAQPNYQSLNGNGAQMLI 210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GDAP1NP_061845.2 GST_N_GDAP1 26..98 CDD:239350 21/71 (30%)
GST_C_GDAP1 179..289 CDD:198336 21/110 (19%)
Required for mitochondrial localization 320..358
GstE9NP_725784.1 GstA 4..201 CDD:223698 56/282 (20%)
GST_N_Delta_Epsilon 4..76 CDD:239343 21/71 (30%)
GST_C_Delta_Epsilon 92..209 CDD:198287 32/192 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154570
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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