Protein Alignment GDAP1 and Gdap1

DIOPT Version :10

• Sequence 1: NP_061845.2
• Gene: GDAP1 / 54332
• HGNCID: 15968
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_034397.1
• Gene: Gdap1 / 14545
• MGIID: 1338002
• Length: 358
• Species: Mus musculus
• Alignment Length: 358
• Identity: 336/358 - (93%)
• Similarity: 343/358 - (95%)
• Gaps: 0/358 - (0%)

Human     1 MAERQEEQRGSPPLRAEGKADAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNE 65
            ||.||:|.|...|||.||..|.||.||||||||||||||||||||||||||||||||||||||||
Mouse     1 MARRQDEARAGVPLRVEGPPDKEVHLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNE 65

Human    66 PWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDS 130
            ||||||||.||||||:|||||||||||||||||||||||||||||||:.||||||||||||||||
Mouse    66 PWFMRLNSAGEVPVLVHGENIICEATQIIDYLEQTFLDERTPRLMPDEGSMYYPRVQHYRELLDS 130

Human   131 LPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSK 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 LPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSK 195

Human   196 LLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKF 260
            |||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||
Mouse   196 LLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGNQPWLCGESFTLADVSLAVTLHRLKF 260

Human   261 LGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLV 325
            |||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||:|||
Mouse   261 LGFARRNWGHGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGSTLV 325

Human   326 VGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF 358
            ||||.|:|||||||||:||||||||.|||||||
Mouse   326 VGLLVGMGYFAFMLFRRRLGSMILALRPRPNYF 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDAP1	NP_061845.2	GST_N_GDAP1	26..98	CDD:239350	69/71 (97%)
		GST_C_GDAP1	179..289	CDD:198336	107/109 (98%)
		Required for mitochondrial localization	320..358		32/37 (86%)
Gdap1	NP_034397.1	GST_N_GDAP1	26..98	CDD:239350	69/71 (97%)
		GST_C_GDAP1	179..289	CDD:198336	107/109 (98%)
		Required for mitochondrial localization. /evidence=ECO:0000250	320..358		32/37 (86%)