Protein Alignment GDAP1 and gdap1

DIOPT Version :10

• Sequence 1: NP_061845.2
• Gene: GDAP1 / 54332
• HGNCID: 15968
• Length: 358
• Species: Homo sapiens
• Sequence 2: XP_002937122.2
• Gene: gdap1 / 100490264
• XenbaseID: XB-GENE-978242
• Length: 350
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 284/339 - (83%)
• Similarity: 317/339 - (93%)
• Gaps: 2/339 - (0%)

Human    20 ADAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGE 84
            |..|.|||||||||||||||||||||||:||||||||||||||||||||||||.:||||||:|||
 Frog    13 AGTEGKLILYHWTHSFSSQKVRLVIAEKSLKCEEHDVSLPLSEHNEPWFMRLNPSGEVPVLVHGE 77

Human    85 NIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVD 149
            |||||||||.|||||||:||:||||:|::.|||||||||||||||||||||||||||||||||||
 Frog    78 NIICEATQITDYLEQTFIDEKTPRLIPEEGSMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVD 142

Human   150 SMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEK 214
            ||||||||:|||:|||:|||||||||:|||||::||||||||||:||.||||:|:|||||:||||
 Frog   143 SMIPAYATSRIRTQIGSTESELKKLAQENPDLEDAYIAKQKRLKTKLQDHDNIKFLKKILEELEK 207

Human   215 VLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETY 279
            ||||||||||||||||||||.:.||||:.|:|||||||||||||:||||||||||||||||||.|
 Frog   208 VLDQVETELQRRNEETPEEGSESWLCGQFFSLADVSLAVTLHRLRFLGFARRNWGNGKRPNLEAY 272

Human   280 YERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRL 344
            |||:|:|||||:|||:||||||||||||||||||||||.:||:||:||||||.|||.|:..||||
 Frog   273 YERILQRKTFNRVLGNVNNILISAVLPTAFRVAKKRAPTILGSTLMVGLLAGAGYFFFLCARKRL 337

Human   345 GSMILAFRPRPNYF 358
            .||.|:.:.:  ||
 Frog   338 FSMFLSIKAK--YF 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GDAP1	NP_061845.2	GST_N_GDAP1	26..98	CDD:239350	66/71 (93%)
		GST_C_GDAP1	179..289	CDD:198336	92/109 (84%)
		Required for mitochondrial localization	320..358		21/37 (57%)
gdap1	XP_002937122.2	GST_N_GDAP1	19..91	CDD:239350	66/71 (93%)
		GST_C_GDAP1	172..282	CDD:198336	92/109 (84%)