DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SNTG2 and Sntg2

DIOPT Version :9

Sequence 1:	XP_016859850.1	Gene:	SNTG2 / 54221	HGNCID:	13741	Length:	540	Species:	Homo sapiens
Sequence 2:	XP_006240029.1	Gene:	Sntg2 / 298936	RGDID:	1311276	Length:	540	Species:	Rattus norvegicus

Alignment Length:	539	Identity:	441/539 - (81%)
Similarity:	482/539 - (89%)	Gaps:	2/539 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     4 SIYSADSAACFTRRTWHQLF-EQTKTTIALLYDEESENAYDIRLKLTKEVLTIQKQDVVCVGGSH 67
            |...:.|.|....|..|.|. .:|||.:||||||..|||||:||||||||||||||||||:||:.
  Rat     2 SAEGSQSLAAPRGRPSHLLVPARTKTALALLYDEGLENAYDVRLKLTKEVLTIQKQDVVCIGGAP 66

Human    68 QGRNRRTVTLRRQPVGGLGLSIKGGSEHNVPVVISKIFEDQAADQTGMLFVGDAVLQVNGIHVEN 132
            .|.|.||||||||||||||||||||:||.|||||||||:|||||||.|||:||||||||||:|||
  Rat    67 PGANHRTVTLRRQPVGGLGLSIKGGAEHGVPVVISKIFKDQAADQTEMLFIGDAVLQVNGINVEN 131

Human   133 ATHEEVVHLLRNAGDEVTITVEYLREAPAFLKLPLGSPGPSSDHSSGASSPLFDSGLHLNGNSST 197
            |||||||||||||||.||||||||||||:|||||||||||||||||.||||||||||||||:.|.
  Rat   132 ATHEEVVHLLRNAGDVVTITVEYLREAPSFLKLPLGSPGPSSDHSSRASSPLFDSGLHLNGHCSH 196

Human   198 TAPSSPSSPIAKDPRYEKRWLDTLSVPLSMARISRYKAGTEKLRWNAFEVLALDGVSSGILRFYT 262
            |||||||||||.:|:|||||||||||||||||||||||||||||.:|.|||||||.|:|.|:|.|
  Rat   197 TAPSSPSSPIANEPKYEKRWLDTLSVPLSMARISRYKAGTEKLRSSALEVLALDGASTGALQFST 261

Human   263 AQDGTDWLRAVSANIRELTLQNMKMANKCCSPSDQVVHMGWVNEKLQGADSS-QTFRPKFLALKG 326
            |||..|||||:|.||.|||||:||||||||||.|||||||||||:|||||:: |.||.|||||:|
  Rat   262 AQDCADWLRAISTNINELTLQHMKMANKCCSPCDQVVHMGWVNERLQGADNNPQNFRSKFLALRG 326

Human   327 PSFYVFSTPPVSTFDWVRAERTYHLCEVLFKVHKFWLTEDCWLQANLYLGLQDFDFEDQRPYCFS 391
            .|||:||.|||||.||.||||.|:|||||||||||||:::.||||||||||||.|.||.|.||||
  Rat   327 SSFYIFSAPPVSTLDWGRAERAYNLCEVLFKVHKFWLSDNYWLQANLYLGLQDLDCEDPRSYCFS 391

Human   392 IVAGHGKSHVFNVELGSELAMWEKSFQRATFMEVQRTGSRTYMCSWQGEMLCFTVDFALGFTCFE 456
            ::|.|||||:|:||||:|||:|||:||||||||||||||:||:|||||||||||||||||||||:
  Rat   392 VLASHGKSHIFSVELGNELAVWEKAFQRATFMEVQRTGSKTYLCSWQGEMLCFTVDFALGFTCFD 456

Human   457 SKTKNVLWRFKFSQLKGSSDDGKTRVKLLFQNLDTKQIETKELEFQDLRAVLHCIHSFIAAKVAS 521
            ||||||||||||||||||||||||||||||||.|||||||||||||||.||||||||||||||||
  Rat   457 SKTKNVLWRFKFSQLKGSSDDGKTRVKLLFQNPDTKQIETKELEFQDLTAVLHCIHSFIAAKVAS 521

Human   522 VDPGFMDSQSLARKYMYSS 540
            :||.||||||:||:||.||
  Rat   522 LDPAFMDSQSVARRYMCSS 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SNTG2	XP_016859850.1	PDZ_signaling	73..154	CDD:238492	73/80 (91%)
Sntg2	XP_006240029.1	PDZ_signaling	72..153	CDD:238492	73/80 (91%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83679338
Domainoid	1	1.000	670	1.000	Domainoid score	I3872
eggNOG	1	0.900	-	-		E1_KOG3549
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41298
Inparanoid	1	1.050	796	1.000	Inparanoid score	I7557
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG46473
OrthoDB	1	1.010	-	-		D104224at40674
OrthoFinder	1	1.000	-	-		FOG0003391
OrthoInspector	1	1.000	-	-		oto139669
orthoMCL	1	0.900	-	-		OOG6_106123
Panther	1	1.100	-	-	LDO	PTHR10554
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2288
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	17.310