Protein Alignment CSNK1G1 and Asator

DIOPT Version :10

• Sequence 1: NP_001316534.1
• Gene: CSNK1G1 / 53944
• HGNCID: 2454
• Length: 475
• Species: Homo sapiens
• Sequence 2: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 127/481 - (26%)
• Similarity: 223/481 - (46%)
• Gaps: 47/481 - (9%)

Human    26 SRPSGSSSSSGVLMVG----PNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHL 86
            ::.|...:|..:|..|    ..::|.:|||.|.|||:..|::|.|.|.||:|:|..:.....|.:
  Fly   151 AKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKM 215

Human    87 EYRFYKQLGSAGEGLPQVYYFGPCG---KYNAMVLELLGPSLEDLFDLCDR-TFTLKTVLMIAIQ 147
            |....|:|    :|...|..|..||   ::|.:|::|.|.:|.:|.....| .|:|.|.|.:.:|
  Fly   216 EVAVLKKL----QGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQ 276

Human   148 LLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLT 212
            :|..:|.:||...::||:||.||.:||.......| :::|||||::|.....:...| |......
  Fly   277 ILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRV-YMLDFGLARQYTTGTGEVRCP-RAAAGFR 339

Human   213 GTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEA 277
            ||.||.|||.|..:|..|.|||.:|.:|.:.|:.|.|||:.:|..      :::|.||.......
  Fly   340 GTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDK------EQVGLTKEKYDHRI 398

Human   278 LCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHV 342
            |.::.|.::..:|.:::.|.:.::|||..|..||....:::|......||| .:...|.:|::..
  Fly   399 LLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDW-EKVDSTAIGNISA 462

Human   343 DSGASAITRESHTHRDRPSQQQPLRNQNVSSERRGEWEIQPSRQTNTSYLTSHLAADRHGGSVQV 407
            ....|...:..:.|.:.........|.:.:...|...||:.:..|.|..|......|::..:..:
  Fly   463 TGNPSIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKNCNATSL 527

Human   408 VSSTNGELNVDDPTGAHSNAP----ITA----------HAEVEV--VEEAKCIMFHKPWHWSQ-S 455
            .....|.   .:|...|.||.    ||:          :::|.:  ::.|..::..:...::: .
  Fly   528 AQPAKGS---GEPMVQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAPSMIEREDVQYTKLE 589

Human   456 SAVKMKFVVFL------NMNVNFKCI 475
            .....||:...      |:::..|||
  Fly   590 EGAPTKFITMKPNGECDNVDIAAKCI 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1G1	NP_001316534.1	STKc_CK1_gamma	43..331	CDD:271028	96/291 (33%)
		CK1gamma_C	331..429	CDD:463640	17/101 (17%)
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	91/272 (33%)