Protein Alignment CSNK1G1 and CkIalpha

DIOPT Version :10

• Sequence 1: NP_001316534.1
• Gene: CSNK1G1 / 53944
• HGNCID: 2454
• Length: 475
• Species: Homo sapiens
• Sequence 2: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 162/319 - (50%)
• Similarity: 217/319 - (68%)
• Gaps: 23/319 - (7%)

Human    26 SRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRF 90
            |||.        ::||..:||.:|||.|:||::.||.::.:.|.||||:|...:|.|||..|.:.
  Fly    10 SRPE--------IIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKL 66

Human    91 YKQLGSAGEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYV 155
            |:.| |.|.|.|::.:.|....:|.:|::||||||||||:.|.|.||:|||||:..|::.|:||:
  Fly    67 YRIL-SGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYI 130

Human   156 HSKNLIYRDVKPENFL--IGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 218
            |.|..|:||:||:|||  |||..||    :.:|||||||::.||.|:.||.|||.|:|||||||.
  Fly   131 HLKCFIHRDIKPDNFLMGIGRHCNK----LFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYA 191

Human   219 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFP 283
            |||.|||.|||||||:|:||::.|||.||.|||||:||:|.:::|:||.:.|.:||||.||:..|
  Fly   192 SINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSP 256

Human   284 EEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDWV--------GRPIP 334
            .|.:.||.|.|.|.|.|:|||.|||.||..||....:.:||.|||.        |:|.|
  Fly   257 AEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQPNP 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSNK1G1	NP_001316534.1	STKc_CK1_gamma	43..331	CDD:271028	154/297 (52%)
		CK1gamma_C	331..429	CDD:463640	2/4 (50%)
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	145/269 (54%)