Protein Alignment PPIL3 and cyp33

DIOPT Version :10

• Sequence 1: NP_115861.1
• Gene: PPIL3 / 53938
• HGNCID: 9262
• Length: 165
• Species: Homo sapiens
• Sequence 2: NP_523773.1
• Gene: cyp33 / 36984
• FlyBaseID: FBgn0028382
• Length: 300
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 59/316 - (18%)
• Similarity: 112/316 - (35%)
• Gaps: 78/316 - (24%)

Human    68 EHTSLAAVELEKQLQTKDLAPEQDFLTRHTFMETQQVDAVTFEDVAVDFTQEEWTSLDPVQRNLY 132
            :|.:.||...........:.|..|        ..||........:..| ..|...|||
  Fly   245 DHLAHAAAAATSAPSDTSVVPAGD--------GRQQAQPQPLRSIHAD-APEPGHSLD------- 293

Human   133 RDVMLENYQNLATVGGQ-----MFKPSLISWLEKKVELTVIEQGILQEWEM--HLKTKRTALQQD 190
            |||.|::.::..|:..:     ..:.::::.:.::.|:....:.::::...  |..|:..|...|
  Fly   294 RDVPLDDEEDTVTLTAETSSECCSQQTVVAVVAEEEEVEAQAEEVVEDGSSPGHDPTETVAPGSD 358

Human   191 RFWSDMSNGMQLGREHSGG---------EPGDPVQVGAVFSEDSCPQTHSSTSNTGNTFACNLDG 246
            ....|     ::..:.:||         ||||......|..:||.|.:.          .|:|.|
  Fly   359 TTTDD-----EVENDDTGGSDADANDEAEPGDTCTRRTVLGQDSTPSSR----------RCSLGG 408

Human   247 KDFQPLLKETSTEENIVQLNQCVKPLIFTPDVSQKKCTPEKSVE-CSDCGETFVNQLELQTHSSS 310
                    |..||:| .:|.:.:.      :::...|||::..: |.:......|.|:|...
  Fly   409 --------EFETEQN-RRLRRRLS------ELTNNFCTPKQFQQLCDNLDNITDNDLKLLVR--- 455

Human   311 HREKNIHKSEE----CGQASTHPISHGGHVIPTEKKYYECKK-----CEKFFTHPV 357
            ..::.|..:|.    |..:......|....:|   |:.:.||     |:|..:..|
  Fly   456 ELKRKIEFAERMNWLCLSSRPRGPPHRKTSLP---KHTDVKKRFLETCDKTLSDEV 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPIL3	NP_115861.1	cyclophilin	1..158	CDD:469651	17/94 (18%)
cyp33	NP_523773.1	RRM_PPIE	8..82	CDD:409783
		cyclophilin_ABH_like	139..297	CDD:238907	14/67 (21%)