| Sequence 1: | NP_059130.2 | Gene: | DUOX1 / 53905 | HGNCID: | 3062 | Length: | 1551 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001097336.1 | Gene: | Nox / 5740310 | FlyBaseID: | FBgn0085428 | Length: | 1340 | Species: | Drosophila melanogaster |
| Alignment Length: | 1247 | Identity: | 248/1247 - (19%) |
|---|---|---|---|
| Similarity: | 412/1247 - (33%) | Gaps: | 512/1247 - (41%) |
- Green bases have known domain annotations that are detailed below.
|
Human 700 RTLLLKIPKEYDLVLLFNLEEERQAL----VENLRGALKESGLSIQEWELREQ-ELMRAAVTREQ 759
Human 760 RRHLLETF-----FRHLFSQVLDINQADAGTLPLDSSQKVREALT-------------------- 799
Human 800 ----------CELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEE 854
Human 855 KSRLMFRMYDFDGNGLISKDEFIRMLRSFIEISNNCLSKAQLAEVVESMFRESGFQDKEELTWED 919
Human 920 FHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQ 984
Human 985 RLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSCLHQTVQQFKRFIENYRRHIGCVA 1049
Human 1050 VFYAIAG-GLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAASISFMFSYILLTMCRNLITFLR 1113
Human 1114 ETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVNVYLFSISPLSVLSCLF----------P 1168
Human 1169 GLFHDDGSELPQKYYWWFFQTVPGL---TGVVLLLILAIMYVFASHHFRRR-SFRGFWLTHHLYI 1229
Human 1230 LLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDKLVSL-----SRKKVEISVVKAELLPSGVTH 1289
Human 1290 LRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTLTSAP-HEDTLSLHIRAAGPWTTRL------- 1346
Human 1347 --------------REIYSAPT---------------GDRCA----------------------- 1359
Human 1360 ----------------------------------------------------------------- 1359
Human 1360 ---------------------------------------------------------------RY 1361
Human 1362 PK--------------------------------------------------------------- 1363
Human 1364 -------------------------------------------------------------LYLD 1367
Human 1368 GPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK------SSVSCQ-----------VFCK 1415
Human 1416 KIYFIWVTRTQRQFEWLADIIR--EVEEND----HQDLVSVHIYITQLAEKFDLRTTMLYICERH 1474
Human 1475 FQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQVRKIGVFSCGPPGMTKNVEKACQLINRQ 1539
Human 1540 DRTHFSHHYENF 1551 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DUOX1 | NP_059130.2 | Peroxidase-like, mediates peroxidase activity | 26..593 | ||
| An_peroxidase | 30..544 | CDD:281139 | |||
| dual_peroxidase_like | 32..591 | CDD:188652 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 150..172 | ||||
| EFh | 820..881 | CDD:238008 | 23/60 (38%) | ||
| EF-hand_7 | 820..880 | CDD:290234 | 23/59 (39%) | ||
| EF-hand_7 | 857..921 | CDD:290234 | 19/63 (30%) | ||
| EFh | 857..915 | CDD:238008 | 16/57 (28%) | ||
| Interaction with TXNDC11. /evidence=ECO:0000250 | 956..1248 | 68/306 (22%) | |||
| Ferric_reduct | 1091..1226 | CDD:280043 | 42/148 (28%) | ||
| NOX_Duox_like_FAD_NADP | 1277..1551 | CDD:99783 | 102/608 (17%) | ||
| Nox | NP_001097336.1 | FRQ1 | 314..466 | CDD:227455 | 38/152 (25%) |
| EFh | 365..425 | CDD:238008 | 23/59 (39%) | ||
| EFh | 399..462 | CDD:238008 | 19/62 (31%) | ||
| Ferric_reduct | 560..700 | CDD:280043 | 45/155 (29%) | ||
| NOX_Duox_like_FAD_NADP | 744..>819 | CDD:99783 | 32/74 (43%) | ||
| FNR_like | <1136..>1178 | CDD:297884 | 18/41 (44%) | ||
| NAD_binding_6 | 1158..1325 | CDD:285298 | 55/168 (33%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0039 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||