Sequence 1: | NP_059130.2 | Gene: | DUOX1 / 53905 | HGNCID: | 3062 | Length: | 1551 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001262653.1 | Gene: | Irc / 42049 | FlyBaseID: | FBgn0038465 | Length: | 697 | Species: | Drosophila melanogaster |
Alignment Length: | 578 | Identity: | 148/578 - (25%) |
---|---|---|---|
Similarity: | 232/578 - (40%) | Gaps: | 114/578 - (19%) |
- Green bases have known domain annotations that are detailed below.
Human 36 YNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-----------------LPN-----PRDL 78
Human 79 SNTISRGPAGLASLRNRTVLGVFFGYHVLSDLVSVETPGCPAEFLNIRIPPGDP-----MFDPDQ 138
Human 139 RGDV--VLPFQRSRW---DPETGRSPSNPRDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLA 198
Human 199 SGPDPAFPRDSQNPLLMWAAPDP-ATGQNGPR----------GLYAFGAERGNREPFLQALGLLW 252
Human 253 FRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL-QKTLPEYTGYRPFLDP 316
Human 317 SISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSSV--SRALRVCNSYWSREH---PSLQ 376
Human 377 -SAEDVDALLLGMASQIAEREDHVLVEDVRDFWPGPLKFSRTDHLASCLQRGRDLG-LPSYTKAR 439
Human 440 AALGLSPITRWQDINPALSRSNDTVLEATAALYNQDLSW--LELLPGGLLES--HRDPGPLFSTI 500
Human 501 VLEQFVRLRDGDRYWFENTRNGLFSKKE-IEEIRNTTLQDVLVAVINIDPSALQPNVF 557 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
DUOX1 | NP_059130.2 | Peroxidase-like, mediates peroxidase activity | 26..593 | 148/578 (26%) | |
An_peroxidase | 30..544 | CDD:281139 | 143/563 (25%) | ||
dual_peroxidase_like | 32..591 | CDD:188652 | 148/578 (26%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 150..172 | 5/24 (21%) | |||
EFh | 820..881 | CDD:238008 | |||
EF-hand_7 | 820..880 | CDD:290234 | |||
EF-hand_7 | 857..921 | CDD:290234 | |||
EFh | 857..915 | CDD:238008 | |||
Interaction with TXNDC11. /evidence=ECO:0000250 | 956..1248 | ||||
Ferric_reduct | 1091..1226 | CDD:280043 | |||
NOX_Duox_like_FAD_NADP | 1277..1551 | CDD:99783 | |||
Irc | NP_001262653.1 | An_peroxidase | 151..672 | CDD:281139 | 143/566 (25%) |
An_peroxidase_like | 290..637 | CDD:265428 | 107/369 (29%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |