Protein Alignment FGFRL1 and CG31431

DIOPT Version :9

• Sequence 1: XP_024309860.1
• Gene: FGFRL1 / 53834
• HGNCID: 3693
• Length: 527
• Species: Homo sapiens
• Sequence 2: NP_001247231.1
• Gene: CG31431 / 326138
• FlyBaseID: FBgn0051431
• Length: 361
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 79/346 - (22%)
• Similarity: 128/346 - (36%)
• Gaps: 90/346 - (26%)

Human   182 VIARPVGSSVRLKCVASG------------------------HPRPDI---TWMKDDQALTRPEA 219
            :|.:..|..|:|:|...|                        |....:   |.:..:.:|.|||
  Fly    40 LIQQRAGFDVKLQCNLKGLVDESMLNDIKIHWYFKQCSENNCHQLGSVDEWTALPCEPSLCRPE- 103

Human   220 AEPRKKKWTLSLKNLRPEDSGKYTCRVS----NRAGAINA----TYKVDVIQRTRSKPVLTGTHP 276
                     |.|:|:....||.|.|.::    ::|.|::.    ||::||...:.:.|....::|
  Fly   104 ---------LWLRNVTERYSGLYKCSINPHIWDKAQAVDVQLVRTYQLDVKNTSLAAPEFVDSYP 159

Human   277 VNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEY-----GAEGR--------HNSTIDVGGQKFVV 328
            .|.|...|....|||:|.|:..|.|:|.:|..|     |.|..        .|..:...|:.:.:
  Fly   160 NNKTTLVGSRVVFQCRVHSEEHPTIKWFRRQTYVGTQSGGEASSAPTTSNFSNHIVRYNGRTYEL 224

Human   329 LPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPD------------ 381
            |.|..........||:||::...|..|||.|.|:..:..|:..|.|||.||.|
  Fly   225 LSTDPEKMMAPQIYLSKLILDGVRLRDAGHYACVAISYRGHKIREAFLDVLADVEDTDQENEYWS 289

Human   382 ---PKPPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPP 443
               .:..|.|.:....     :.::..:|.|...:  .|.:|......|.|:       .||
  Fly   290 DYGNEDEGVPTSDRRE-----FLLLFLMPLGLALL--PLTVWFSYLLYKRCS-------VGH--- 337

Human   444 GTARDRSGDKDLPSLAALSAG 464
            |..:....|:||.:...:..|
  Fly   338 GDCQRIDSDEDLDTERCVLGG 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGFRL1	XP_024309860.1	I-set	56..139	CDD:254352
		Ig2_FGFRL1-like	180..261	CDD:143264	23/113 (20%)
		Ig	284..378	CDD:325142	32/106 (30%)
CG31431	NP_001247231.1	IG_like	159..274	CDD:214653	35/114 (31%)
		Ig	167..275	CDD:299845	32/107 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143159
Domainoid	1	1.000	47	1.000	Domainoid score	I12100
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7169
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19890
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.890