Protein Alignment GPR84 and Octbeta2R

DIOPT Version :10

• Sequence 1: NP_065103.1
• Gene: GPR84 / 53831
• HGNCID: 4535
• Length: 396
• Species: Homo sapiens
• Sequence 2: NP_001163596.2
• Gene: Octbeta2R / 41549
• FlyBaseID: FBgn0038063
• Length: 630
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 82/370 - (22%)
• Similarity: 149/370 - (40%)
• Gaps: 62/370 - (16%)

Human    28 VVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATF 92
            :::.:....||:|.::::....|||...|..:.:|.:||::...:...|:....:...|......
  Fly   161 LLIIIAAICGNLLVIISVMRVRKLRVITNYFVVSLAMADIMVAIMAMTFNFSVQVTGRWNFSPFL 225

Human    93 CRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWV-VGVASFAPLW 156
            |.::..|....::.|||.||.|::.||..|..|..:|...:.:.:.:.|::||: ..:.||.|::
  Fly   226 CDLWNSLDVYFSTASILHLCCISVDRYYAIVKPLKYPISMTKRVVGIMLLNTWISPALLSFLPIF 290

Human   157 PIYILVP-----VV---CTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALD 213
            ..:...|     |:   ..|||  :..:.|..|...|.|.:..:.:...|..|.|:..|..:.|.
  Fly   291 IGWYTTPQHQQFVIQNPTQCSF--VVNKYYAVISSSISFWIPCTIMIFTYLAIFREANRQEKQLM 353

Human   214 QYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQI 278
            ........:|...:..:.||:.|          ||            ::.|.||.    ||..:.
  Fly   354 MRHGNAMLMHRPSMQPSGEALSG----------SG------------SSKTLTLH----EVEQEH 392

Human   279 NSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDA 343
            ...:.|.:              ||..|.        .|..|....:...|.|.::||.|...|..
  Fly   393 TPTKDKHL--------------IKMKRE--------HKAARTLGIIMGTFILCWLPFFLWYTLSM 435

Human   344 RVQAPRVVHMLAANLTWL---NGCINPVLYAAMNRQFRQAYGSIL 385
            ..:..:|..::.:.|.|:   |..:||::||..||.||:|:.:.|
  Fly   436 TCEECQVPDIVVSILFWIGYFNSTLNPLIYAYFNRDFREAFRNTL 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPR84	NP_065103.1	7tmA_GPR84-like	21..381	CDD:320338	80/364 (22%)
		TM helix 1	22..48	CDD:320338	3/19 (16%)
		TM helix 2	55..78	CDD:320338	5/22 (23%)
		TM helix 3	93..123	CDD:320338	10/29 (34%)
		TM helix 4	137..155	CDD:320338	5/18 (28%)
		TM helix 5	175..200	CDD:320338	5/24 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..311		11/66 (17%)
		TM helix 6	312..342	CDD:320338	7/29 (24%)
		TM helix 7	349..374	CDD:320338	8/27 (30%)
Octbeta2R	NP_001163596.2	7tmA_DmOct-betaAR-like	155..476	CDD:320194	80/364 (22%)
		TM helix 1	155..181	CDD:320194	3/19 (16%)
		TM helix 2	188..214	CDD:320194	5/25 (20%)
		TM helix 3	226..256	CDD:320194	10/29 (34%)
		TM helix 4	268..291	CDD:320194	6/22 (27%)
		TM helix 5	315..344	CDD:320194	6/28 (21%)
		TM helix 6	404..434	CDD:320194	8/37 (22%)
		TM helix 7	444..469	CDD:320194	7/24 (29%)