Protein Alignment PMM2 and pmm1

DIOPT Version :10

• Sequence 1: NP_000294.1
• Gene: PMM2 / 5373
• HGNCID: 9115
• Length: 246
• Species: Homo sapiens
• Sequence 2: NP_594325.1
• Gene: pmm1 / 2541674
• PomBaseID: SPAC1556.07
• Length: 257
• Species: Schizosaccharomyces pombe
• Alignment Length: 239
• Identity: 141/239 - (58%)
• Similarity: 173/239 - (72%)
• Gaps: 5/239 - (2%)

Human     8 LCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQL---GNDVVEKYDYVFP 69
            |.|||||||||..|..::.||.:.||.||:.:.||.|||||..|.||||   |.:|::.:||.|.
pombe    15 LVLFDVDGTLTPARLSVSPEMLETLQNLRKVVAIGFVGGSDLSKQQEQLSVNGENVIDSFDYAFA 79

Human    70 ENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGR 134
            ||||.||:.|:.|..|:..:.|||...|.|:|:||.|||.:.:|.||||||||||||:|:||:||
pombe    80 ENGLTAYRYGQQLASQSFIAWLGEEKYQKLVNFCLHYIADLDIPVKRGTFIEFRNGMINISPVGR 144

Human   135 SCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVEND 199
            :.:.|||.||...||...||...|..||::|...||||||||||||||||.||||.|||:|||.:
pombe   145 NANTEERNEFERFDKGRKIRATMVDVLREKFKDYGLTFSIGGQISFDVFPAGWDKTYCLQHVEKE 209

Human   200 GYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICEL 243
            |:.||:||||||..||||:|||.||||:|:|||.|:||  |.||
pombe   210 GFDTIHFFGDKTYKGGNDYEIFVDPRTIGHSVTNPDDT--IAEL 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMM2	NP_000294.1	HAD_PMM	8..244	CDD:319784	141/239 (59%)
pmm1	NP_594325.1	OtsB	12..>48	CDD:441481	17/32 (53%)
		PMM	35..257	CDD:397425	129/219 (59%)