Protein Alignment PMM2 and pmm1

DIOPT Version :10

• Sequence 1: NP_000294.1
• Gene: PMM2 / 5373
• HGNCID: 9115
• Length: 246
• Species: Homo sapiens
• Sequence 2: NP_001106421.1
• Gene: pmm1 / 100127589
• XenbaseID: XB-GENE-974466
• Length: 246
• Species: Xenopus tropicalis
• Alignment Length: 238
• Identity: 181/238 - (76%)
• Similarity: 218/238 - (91%)
• Gaps: 0/238 - (0%)

Human     8 LCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENG 72
            ||||||||||||.|||:||:|.:||::||:::|:||||||||||::||||:|||||:||||.|||
 Frog     7 LCLFDVDGTLTAARQKVTKDMAEFLEELRKRVKVGVVGGSDFEKIKEQLGDDVVEKFDYVFAENG 71

Human    73 LVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCS 137
            ||||||||.||:|:|.:||||.|:||:||||||||||:|||||||||:||||||||||||||:|:
 Frog    72 LVAYKDGKFLCKQSIHAHLGEDLLQDIINYCLSYIAKLKLPKKRGTFVEFRNGMLNVSPIGRNCT 136

Human   138 QEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYK 202
            ||||||||||||||..|.||||:|::||:|:||||||||||||||||.||||.:||..:||:|:.
 Frog   137 QEERIEFYELDKKEQFRDKFVAELQREFSGRGLTFSIGGQISFDVFPTGWDKTFCLGILENEGFS 201

Human   203 TIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLF 245
            .||||||||||||||:||:||.||:|:|||:|.:||.||..||
 Frog   202 KIYFFGDKTMPGGNDYEIYTDSRTIGHSVTSPGETRTICTELF 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PMM2	NP_000294.1	HAD_PMM	8..244	CDD:319784	179/235 (76%)
pmm1	NP_001106421.1	HAD_PMM	7..243	CDD:319784	179/235 (76%)