Protein Alignment Gnpat and Gpam

DIOPT Version :10

• Sequence 1: NP_001262957.1
• Gene: Gnpat / 53586
• FlyBaseID: FBgn0040212
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_036017329.1
• Gene: Gpam / 14732
• MGIID: 109162
• Length: 844
• Species: Mus musculus
• Alignment Length: 904
• Identity: 187/904 - (20%)
• Similarity: 341/904 - (37%)
• Gaps: 271/904 - (29%)

  Fly     7 RQSTSSGTVEGESSEQEEQKT---------PSAAEYMRN------------------FKNIIAPG 44
            :|..:.|.....|:.:|...|         ||::||...                  |::.....
Mouse     4 QQPAAHGLGLARSAMEESSVTVGTIDVSYLPSSSEYSLGRCKHTSEDWVDCGFKPTFFRSATLKW 68

  Fly    45 NEASMTRE--FNPQVAY-----EFEKYLNPQ---------------------------------- 68
            .|:.|:|:  |..:..|     .:|::.||.
Mouse    69 KESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQ 133

  Fly    69 -----------KLKQHVLRSEKLRSILEHYAKE---------SGTPLKQMERQARAIIDEIGLDR 113
                       .:.::||.|.:::..:...|.|         ....:::::|:||.|:.|:....
Mouse   134 ERDVHKGMFATSVTENVLSSSRVQEAIAEVAAELNPDGSAQQQSKAIQKVKRKARKILQEMVATV 198

  Fly   114 NMAIIRWCGIAITAIGKRICDGFY------------VNSASMANVRKDMGKCPVLYLPSHRSYMD 166
            :..:||..|..:.    ::.:.|:            |.:|:..|:       |:|:||.|||::|
Mouse   199 SPGMIRLTGWVLL----KLFNSFFWNIQIHKGQLEMVKAATETNL-------PLLFLPVHRSHID 252

  Fly   167 FILMSYICYYYDIEIPGIAAGMDFH-SMFGMGTMLRKTGAFFMRRSFS------NDELYWDIFRE 224
            ::|:::|.:.::|:.|.||:|.:.: .:|  .|::.|.|.||:||...      .|.||..:...
Mouse   253 YLLLTFILFCHNIKAPYIASGNNLNIPVF--STLIHKLGGFFIRRRLDETPDGRKDILYRALLHG 315

  Fly   225 YMYALVANYHIGVEFFIEGTRSRNFKALVPKIGLLSMALLPYFTGEVPDVMIVPVSVAYERVLEE 289
            ::..|:..... :|.|:||||||:.|....:.||||:.:....:..:||::::||.::|:|::|.
Mouse   316 HVVELLRQQQF-LEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEG 379

  Fly   290 QLFVYELLGVPKPKES----TKGFFKALKIIDERFGKMFLDFGEPISVKEFFGHDSAQ------R 344
            . :..|.||.||..||    .:|..:.|:   :.:|.:.:||.:|.|:||:....|.:      .
Mouse   380 H-YNGEQLGKPKKNESLWSVARGVIRMLR---KNYGYVRVDFAQPFSLKEYLEGQSQKPVSAPLS 440

  Fly   345 MQRA-----------GVGGHLQKLNRQEV----------ELVKQLANEIIYQQQRRIVISTFNL- 387
            :::|           .|....|.|:..|.          .|:..||..|::...:...|.:.::
Mouse   441 LEQALLPAILPSRPNDVADEHQDLSSNESRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIV 505

  Fly   388 --LSLY------YASQLYAQRSVTLDE-LARG------------VLHLKRIFEQLG-----AHVS 426
              |.||      :.|.|.....|..:| |||.            |:|   ..:.||     .|.|
Mouse   506 ACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMH---AIQLLGNCVTITHTS 567

  Fly   427 ------TTPSSIKADVIDAVEIHSN-ILH------------FATGRLQFTPMAAKQLAEQIDVKR 472
                  .|||:....|.: :..:|| :||            :|....:.:..:|..|...|..::
Mouse   568 RKDEFFITPSTTVPSVFE-LNFYSNGVLHVFIMEAIIACSIYAVLNKRCSGGSAGGLGNLISQEQ 631

  Fly   473 L--KAHALCPQTMAVAVPMLALQLYINPCMFWLARPAYLLLAALKEQKNQQKQSTDIS---YDAS 532
            |  ||.:||..........|..|.:...|...:.:.....:..:.||.:|:..|..::   :|..
Mouse   632 LVRKAASLCYLLSNEGTISLPCQTFYQVCHETVGKFIQYGILTVAEQDDQEDVSPGLAEQQWDKK 696

  Fly   533 LCALH--AHVTTMDALFQHE-----FIIESNREAAEFETHLQLLLDERVVEVETSGRINVQDNEC 590
            |..|:  :.....|:.|..|     ..:..::|..:|.|.||.||.. ::|..:|..|.|.:
Mouse   697 LPELNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGP-LLEAYSSAAIFVHN--- 757

  Fly   591 SHVILAALAPFLCLYYQLVVTLRKIPLELEFSNKELLVRVQQHVEQLLQQPGASASHVHPYCLAL 655
                                          ||..   |...:::::|           |.|.:..
Mouse   758 ------------------------------FSGP---VPESEYLQKL-----------HRYLITR 778

  Fly   656 DNLNIAIYALIQRGYLVKS-----RDSGQMKIASTPGKCLRELETQLLEYCQLMPFAQY 709
            ...|:|:||......|||:     :|.|..|........:.||.:..|..|......:|
Mouse   779 TERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRVSVLELSSTFLPQCNRQKLLEY 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gnpat	NP_001262957.1	PlsB	63..684	CDD:442180	166/787 (21%)
		LPLAT_DHAPAT-like	133..338	CDD:153255	67/227 (30%)
Gpam	XP_036017329.1	PlsB	146..673	CDD:442180	127/548 (23%)
		LPLAT_DHAPAT-like	218..428	CDD:153255	66/223 (30%)