Protein Alignment Dhap-at and Gnpat

DIOPT Version :9

• Sequence 1: NP_001262957.1
• Gene: Dhap-at / 53586
• FlyBaseID: FBgn0040212
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_034452.3
• Gene: Gnpat / 14712
• MGIID: 1343460
• Length: 678
• Species: Mus musculus
• Alignment Length: 666
• Identity: 201/666 - (30%)
• Similarity: 336/666 - (50%)
• Gaps: 76/666 - (11%)

  Fly    67 PQKLKQHVLRSEKLRSILEHYAKESGTPLKQMERQARAIIDEIGLDRNMAIIRWCGIAITAIGKR 131
            |..:|..||.||::..:::..::||.|.:..:..:|..|::|:.....:..||:....::.|.|:
Mouse    67 PGDIKSIVLSSEEINYVIKQLSRESLTGVDVLREEASEILEEMSHKLRIGAIRFFAFVLSKIFKQ 131

  Fly   132 ICDGFYVNSASMANVRKDMGKCPVLYLPSHRSYMDFILMSYICYYYDIEIPGIAAGMDFHSMFGM 196
            |.....||...:..:::.:.:.||:.|||||||:||:::|:|.|.||:.:|.|||||||..|..:
Mouse   132 IFSKVCVNEEGIQKLQRAVQEHPVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLGMRVV 196

  Fly   197 GTMLRKTGAFFMRRSFSNDELYWDIFREYMYALVANYHIGVEFFIEGTRSRNFKALVPKIGLLSM 261
            ..:||.:|||||||:|..::|||.:|.||:..::...:..||||:||||||..|.|.||.|||::
Mouse   197 SELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRCGYAPVEFFLEGTRSRAAKTLTPKFGLLNI 261

  Fly   262 ALLPYFTGEVPDVMIVPVSVAYERVLEEQLFVYELLGVPKPKESTKGFFKALKIIDERFGKMFLD 326
            .:.|:|..||.|...||:|::|:::|||.|:.||:||||||||||.|..||.:|:.|.||.:.:.
Mouse   262 VMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKARRILSENFGSIHVY 326

  Fly   327 FGEPISVKEFFGHDSAQRMQRAGVGGHLQKLNRQEVELVKQLANEIIYQQQRRIVISTFNL-LS- 389
            ||:|:|::..    :|.|:.|.......:.:.:::.|.|:....|:.|:.|   ::...|| ||
Mouse   327 FGDPVSLRSL----AAGRLNRNTYNLVPRCIPQKQPEDVQAFVTEVAYKMQ---LLQIENLALSP 384

  Fly   390 --LYYASQLYAQRSVTLDELARGVLHLKRIFEQLGAHVSTTPSSIKADVI-DAVEIHSNILHFAT 451
              |.....|..|.|:..|.|....|.||.:.:..|..:....:.:..:|: .::.:|||:
Mouse   385 WLLVVTILLQNQLSMDFDALVEKTLWLKGVTQVFGGFLLWPDNKLPEEVVQSSILLHSNL----- 444

  Fly   452 GRLQFTPMAAKQLAEQIDVKRLK-----AHALCPQTMAVAVPMLALQLYINPCMFWLARPAYLLL 511
                     |..:.:|:.:|...     .:.|.|:.:|    :|....|.|..:...|||: |:.
Mouse   445 ---------ASLVKDQVVLKMNSGSSQVVNGLVPEHIA----LLMCSAYRNQLLNIFARPS-LVA 495

  Fly   512 AALKEQKNQQKQSTDISYDASLCALHAHVTTMDALFQHEFIIESNREAAEFETHLQLLLDERVVE 576
            .||......:|:      |...|     .:.:..:|..|||........:||....||.....::
Mouse   496 LALHMTPGLRKE------DVFSC-----FSFLRNVFSDEFIFLPGNTLRDFEEGCYLLCKAEAMQ 549

  Fly   577 VETSGRINVQDNECSHVI--LAAL-APF------LCLYYQLVVTLRKIPLELEFSNKELLVRVQQ 632
            :  :|:..:..::.:.|:  |.:| .||      ||.|.        :..|..|..||.||..::
Mouse   550 M--AGKDIILTDKGTAVLQFLTSLFKPFVESYQLLCRYL--------LHEEDYFGEKEYLVAARK 604

  Fly   633 HVEQLLQQPGASASHVHPYCLALDNLNIAIYALIQRGYLVKSR-DSGQMKIASTPGKCLRELETQ 696
            ...|||.| |:|..:   ..|:.:....|:.|.::.|.:.|.: ||..:...:  |....:||..
Mouse   605 FTRQLLDQ-GSSQCY---DALSSELQKNALAAFVRLGVVEKKKVDSKYVYYVN--GPATSKLEEM 663

  Fly   697 LLEYCQLMPFAQYSTA 712
            |  .|: .|..:.:||
Mouse   664 L--GCK-KPIGKPATA 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dhap-at	NP_001262957.1	LPLAT_DHAPAT-like	133..338	CDD:153255	96/204 (47%)
Gnpat	NP_034452.3	LPLAT_DHAPAT-like	133..338	CDD:153255	96/208 (46%)
		HXXXXD motif	161..166		4/4 (100%)
		Microbody targeting signal. /evidence=ECO:0000255	676..678		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849901
Domainoid	1	1.000	142	1.000	Domainoid score	I4686
eggNOG	1	0.900	-	-		E1_COG2937
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40716
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3173
Isobase	1	0.950	-	0	Normalized mean entropy	S5763
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D129142at33208
OrthoFinder	1	1.000	-	-		FOG0003976
OrthoInspector	1	1.000	-	-		oto95435
orthoMCL	1	0.900	-	-		OOG6_103425
Panther	1	1.100	-	-	LDO	PTHR12563
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3282
SonicParanoid	1	1.000	-	-		X2733
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740