Protein Alignment Gnpat and gpam

DIOPT Version :10

• Sequence 1: NP_001262957.1
• Gene: Gnpat / 53586
• FlyBaseID: FBgn0040212
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: XP_009305069.1
• Gene: gpam / 100332911
• ZFINID: ZDB-GENE-101026-1
• Length: 826
• Species: Danio rerio
• Alignment Length: 888
• Identity: 181/888 - (20%)
• Similarity: 341/888 - (38%)
• Gaps: 268/888 - (30%)

  Fly     4 NPVRQSTSSGTVEGESSEQEEQKTPSA--------AEYMRNFK--------NIIAPGNEASMTRE 52
            ||   .|.|..::....:|:...:||.        .|.:.|.|        :...|   .|..|.
Zfish    18 NP---DTGSACLKHPCEDQDRSSSPSVLRCVTTTWKEGLLNRKRPFVGRCCHSCTP---QSQDRL 76

  Fly    53 FNPQV--------------------------AY-------EFEKYLNPQKLKQHVLRSEKLRSIL 84
            |||.:                          :|       :.:|.:..:.:.::||.:.:|...:
Zfish    77 FNPSIPSLGLRNVIYINETHTRHRGWLARRLSYVLFVLERDVQKDMFARNVVENVLNNSRLECAI 141

  Fly    85 EHYA----KESGTP------LKQMERQARAIIDEIGLDRNMAIIRWCGIAITAIGKRICDGFY-- 137
            ...|    :|...|      :.::.|:||..:.|:..:.:.|:||..|..:.    ::.:||:
Zfish   142 VEVANEGVQEDAEPGVDPKAVSKVRRKARGWLQEMVANISPALIRLTGWVLL----KLFNGFFWS 202

  Fly   138 --VNSASMANVRKDMGK--CPVLYLPSHRSYMDFILMSYICYYYDIEIPGIAAGMDFHSMFGMGT 198
              ::...:..|:|...:  .|:::||.|:|::|::|:::|.:.::|:.|.||||.:.:... :.|
Zfish   203 IQIHKGQLEMVKKAASEYNAPLVFLPVHKSHIDYLLITFILFCHNIKAPHIAAGNNLNIPI-LST 266

  Fly   199 MLRKTGAFFMRRSF------SNDELYWDIFREYMYALVANYHIGVEFFIEGTRSRNFKALVPKIG 257
            ::||.|.||:||..      ..|.||..:...|...|:..... :|.::||||||:.|....:.|
Zfish   267 LIRKLGGFFIRRKMDETSDGKKDVLYRSLLHAYTEELLRQQQF-LEVYLEGTRSRSGKPSPARAG 330

  Fly   258 LLSMALLPYFTGEVPDVMIVPVSVAYERVLEEQLFVYELLGVPKPKES----TKGFFKALKIIDE 318
            :||:.:.......:|||:||||.::|:|::|.. :..|.||.||..||    ..|.|:.|:   :
Zfish   331 MLSIVVDTLCASTIPDVLIVPVGISYDRIIEGN-YNSEQLGKPKKNESLWGIACGVFRMLR---K 391

  Fly   319 RFGKMFLDFGEPISVKEFFGHDSAQRMQ-------------------RAGVGG----HLQKLNRQ 360
            .:|.:.:||.:|.|:||:.....::.:|                   :|...|    ||......
Zfish   392 NYGCVRVDFTQPFSLKEYLDTQRSRHLQASLTLEQILLPIIIATQPDQAVFNGENENHLNSDLSD 456

  Fly   361 EV---ELVKQLANEIIYQQQRRIVISTFNLLSLYYASQLYAQR-SVTLDELARGVLHLK-----R 416
            |.   :::..||..:::...:...|.:.::::...   ||..| .|.|.:|.....::|     |
Zfish   457 EPWRRQVIADLAKHVLFSASKSSAIMSTHIVACLL---LYRHRQGVLLSKLVEDFFNMKEEILSR 518

  Fly   417 IFE----------------QLGAHVSTTPSSIKADVIDA----------VEIHSN-ILH------ 448
            .|:                .||..|:.|.::...:.|.:          :..:|| :.|
Zfish   519 DFDLGFSGNSEDVVMHALSLLGNCVNVTSTNKNTEFIISPSNTVPALFELNFYSNGLFHVFIADA 583

  Fly   449 -FATGRL----QFTPMAAKQ-------LAEQIDVKRLK--AHALCPQTMAVAVPMLALQLYINPC 499
             .|...|    :.||.:|.:       |:::..::|..  :|.|..: :|||:|...|....:..
Zfish   584 IIACSALALLREQTPASASEQNPSSTLLSQERLIRRAAGLSHFLSNE-VAVALPCQTLYQVFHDA 647

  Fly   500 MFWLARPAYLLLA--------------------ALKEQKNQQKQSTDISYDASLCALHAHVTTMD 544
            :..|.....|::|                    ||..:.:::.:.:|..               |
Zfish   648 ITRLIEYGVLIVAEEDQEELSPSEEPWPKKFPEALSWRSDEEDEDSDFG---------------D 697

  Fly   545 ALFQHEFIIESNREAAEFETHLQLLLDERVVEVETSGRINVQDNECSHVILAALAPFLCLYYQLV 609
            ........:..:.|..||.|.||.:|.. |:|..:...|.:      |.:.:.::
Zfish   698 EQRDRYLKVSPSAEHQEFYTFLQRILTP-VLEAYSGAAIFI------HSLTSPIS---------- 745

  Fly   610 VTLRKIPLELEFSN---KELLVRVQQHVEQLLQQPGASASHVHPYCLALDNLNIAIYALIQRGYL 671
                    |.::::   |.||.|.::.|...    |.||:|                      ||
Zfish   746 --------ERDYTHQLFKYLLTRTERGVSMY----GESATH----------------------YL 776

  Fly   672 VKS-----RDSGQMKIASTPGKCLRELETQLLEYCQLMPFAQY 709
            ||:     ::.|.:|.....|.|..||.:..:.........||
Zfish   777 VKNTVKTFKELGVLKERREDGVCRLELSSTFIPQANKNKLLQY 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gnpat	NP_001262957.1	PlsB	63..684	CDD:442180	158/753 (21%)
		LPLAT_DHAPAT-like	133..338	CDD:153255	69/220 (31%)
gpam	XP_009305069.1	PlsB	103..676	CDD:442180	128/586 (22%)
		LPLAT_DHAPAT-like	200..411	CDD:153255	67/216 (31%)