Protein Alignment Debcl and BCL2L14

DIOPT Version :9

• Sequence 1: NP_788278.1
• Gene: Debcl / 53585
• FlyBaseID: FBgn0029131
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001357197.1
• Gene: BCL2L14 / 79370
• HGNCID: 16657
• Length: 327
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 48/265 - (18%)
• Similarity: 93/265 - (35%)
• Gaps: 79/265 - (29%)

  Fly    37 SDWKALRGGVGGGAGGPGSVPNPSNGRSLHAGGPMTRAASTSSLASSTRTMTNYQ---EYK---- 94
            |.|||..|.|       ....:.|....:.|.|..|.....|.....:|.::|.:   |::
Human    91 SSWKAFFGVV-------EKEDSQSTPAKVSAQGQRTLEYQDSHSQQWSRCLSNVEQCLEHEAVDP 148

  Fly    95 --MDIINQGKCLCGQYIRARLRRAGVLNRK---VTQ----RLRNILDPGSS-------HVVYEVF 143
              :.|.|:...:...:...:..:||....|   ||:    :|:..:...||       .::.::.
Human   149 KVISIANRVAEIVYSWPPPQATQAGGFKSKEIFVTEGLSFQLQGHVPVASSSKKDEEEQILAKIV 213

  Fly   144 PALNSMGEELER---------------MHPRVYTNISRQLSRA--PFGELE---DSDMAPMLLNL 188
            ..|...|::|||               :...|:..|:.|:...  |.||.|   ....|.:::::
Human   214 ELLKYSGDQLERKLKKDKALMGHFQDGLSYSVFKTITDQVLMGVDPRGESEVKAQGFKAALVIDV 278

  Fly   189 VAKDLFRSSITWGKIISIFAVCGGFAIDCVRQGHFDYLQCLIDGLAEIIEDDLVYWLIDNGGW-- 251
            .||.....:....:::       ||.                   .:.::::...|:..:|||
Human   279 TAKLTAIDNHPMNRVL-------GFG-------------------TKYLKENFSPWIQQHGGWEK 317

  Fly   252 -LGLS 255
             ||:|
Human   318 ILGIS 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	32/186 (17%)
BCL2L14	NP_001357197.1	Bcl-2_like	185..319	CDD:351812	24/159 (15%)
		BH3	212..226		4/13 (31%)
		BH2	308..315		2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4728
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810