DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Debcl and Bcl2l2

DIOPT Version :9

Sequence 1:	NP_788278.1	Gene:	Debcl / 53585	FlyBaseID:	FBgn0029131	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	XP_017455282.1	Gene:	Bcl2l2 / 60434	RGDID:	620717	Length:	219	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	44/227 - (19%)
Similarity:	81/227 - (35%)	Gaps:	48/227 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 RAASTSSLASSTRTMTNYQEYKMDIINQGKCLCGQYIRARLRRAGVLNRKVTQRLRNILDPGSSH 137
            |.|:.:|...:...:.::..||   :.|...:||         ||               ||...
  Rat    26 RMATPASTPDTRALVADFVGYK---LRQKGYVCG---------AG---------------PGEGP 63

  Fly   138 VVYEVFPALNSMGEELERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSITWGK 202
            ....:..|:.:.|:|.|....|.:::::.||...|       ..|......|:.:||:....||:
  Rat    64 AADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTP-------GSAQQRFTQVSDELFQGGPNWGR 121

  Fly   203 IISIFAVCGGFAIDCVRQGHFDYLQCLIDGLAEIIEDDLVYWLIDNGGWL---------GLSRHI 258
            :::.|........:.|.:.....:..:.|.:...:|..|..|:..:|||.         .|....
  Rat   122 LVAFFVFGAALCAESVNKEMEPLVGQVQDWMVTYLETRLADWIHSSGGWAEFTALYGDGALEEAR 186

  Fly   259 RPRVGEF-----TFLGWLTLFVTISAGAYMVS 285
            |.|.|.:     ...|.:.|...::.||:..|
  Rat   187 RLREGNWASVRTVLTGAVALGALVTVGAFFAS 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	28/158 (18%)
Bcl2l2	XP_017455282.1	Bcl-2_like	35..173	CDD:132900	32/171 (19%)
		bcl-2	37..219	CDD:273308	41/216 (19%)
		ABATE	146..>205	CDD:284698	12/58 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4728
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810