DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Debcl and bcl2a

DIOPT Version :9

Sequence 1:	NP_788278.1	Gene:	Debcl / 53585	FlyBaseID:	FBgn0029131	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001025424.1	Gene:	bcl2a / 570772	ZFINID:	ZDB-GENE-051012-1	Length:	228	Species:	Danio rerio

Alignment Length:	153	Identity:	37/153 - (24%)
Similarity:	67/153 - (43%)	Gaps:	32/153 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 NQGKCLCGQYIRARLRRAGVLNRKVTQRLRNILDPGSSHVVYEVFPALNSMGEELERMHPRVYTN 163
            |..:||.     ||:.|:               ||   |:  .::..|...|:|:||::.|.:..
Zfish    64 NNSECLI-----ARVTRS---------------DP---HL--RLYRVLRDAGDEIERIYQREFEE 103

  Fly   164 ISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSITWGKIISIFAVCGGFAIDCVRQGHFDYLQC 228
            :|:|:...|       :.|......||::|||..:.||:||:.|...|...::.|.:.....:..
Zfish   104 MSQQMVFNP-------NSAQRSFLTVAEELFRDGVNWGRIIAFFEFGGTMCVESVNREMASQVDN 161

  Fly   229 LIDGLAEIIEDDLVYWLIDNGGW 251
            :...:.:.:...|..|:.:||||
Zfish   162 IAHWMTDYLNGPLENWIEENGGW 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	34/145 (23%)
bcl2a	NP_001025424.1	BH4	6..30	CDD:280361
		bcl-2	9..192	CDD:273308	37/153 (24%)
		Bcl-2_like	65..190	CDD:132900	36/152 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910