DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Debcl and bokb

DIOPT Version :9

Sequence 1:	NP_788278.1	Gene:	Debcl / 53585	FlyBaseID:	FBgn0029131	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_957479.1	Gene:	bokb / 394160	ZFINID:	ZDB-GENE-040426-1346	Length:	211	Species:	Danio rerio

Alignment Length:	180	Identity:	63/180 - (35%)
Similarity:	97/180 - (53%)	Gaps:	9/180 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 ASTSSLASSTRTMTNYQEYKMDIINQGKCLCGQYIRARLRRAGVLNRKVTQRLRNILDPGSSHVV 139
            |.:|.||:....:.:....:.:::.|.|.||..:|.:|:.|.|:...||...|     |....|:
Zfish     5 ARSSVLAAEMIDVFDRTHTEKELVFQSKELCRDFIHSRITREGLSWSKVELDL-----PEPRGVL 64

  Fly   140 YEVFPALNSMGEELERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSITWGKII 204
            .:|...|..:|:|||.|.|.||.||::||:.:...|...||   ..|: ||.::....|||||::
Zfish    65 VDVSVVLLKLGDELECMRPYVYRNIAKQLNISVSVEAVVSD---AFLS-VATEVIAMGITWGKVV 125

  Fly   205 SIFAVCGGFAIDCVRQGHFDYLQCLIDGLAEIIEDDLVYWLIDNGGWLGL 254
            :|:||..|.|:||||.||...:..::|.|.|.:...||.||...|||:.:
Zfish   126 AIYAVAAGLAVDCVRLGHPVMVHTIVDSLGEFVRRSLVPWLKKRGGWVDI 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	55/148 (37%)
bokb	NP_957479.1	Bcl-2_like	29..178	CDD:132900	59/156 (38%)
		BH4	32..44		5/11 (45%)
		BH3	67..83		7/15 (47%)
		BH1	113..132		8/18 (44%)
		BH2	165..179		5/11 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576779
Domainoid	1	1.000	90	1.000	Domainoid score	I7754
eggNOG	1	0.900	-	-		E1_KOG4728
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	103	1.000	Inparanoid score	I4946
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278637at2759
OrthoFinder	1	1.000	-	-		FOG0005475
OrthoInspector	1	1.000	-	-		mtm6365
orthoMCL	1	0.900	-	-		OOG6_108286
Panther	1	1.100	-	-	O	PTHR11256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3895
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.760