Protein Alignment Debcl and Bcl2l2

DIOPT Version :10

• Sequence 1: NP_788278.1
• Gene: Debcl / 53585
• FlyBaseID: FBgn0029131
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_031563.1
• Gene: Bcl2l2 / 12050
• MGIID: 108052
• Length: 193
• Species: Mus musculus
• Alignment Length: 198
• Identity: 38/198 - (19%)
• Similarity: 73/198 - (36%)
• Gaps: 30/198 - (15%)

  Fly   102 KCLCGQYIRARLRRAGVLNRKVTQRLRNILDPGSSHVVYEVFPALNSMGEELERMHPRVYTNISR 166
            :.|...::..:||:.|.:..         ..||.......:..|:.:.|:|.|....|.:::::.
Mouse    11 RALVADFVGYKLRQKGYVCG---------AGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA 66

  Fly   167 QLSRAPFGELEDSDMAPMLLNLVAKDLFRSSITWGKIISIFAVCGGFAIDCVRQGHFDYLQCLID 231
            ||...|       ..|......|:.:||:....||::::.|........:.|.:.....:..:.|
Mouse    67 QLHVTP-------GSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQD 124

  Fly   232 GLAEIIEDDLVYWLIDNGGWL---------GLSRHIRPRVGEF-----TFLGWLTLFVTISAGAY 282
            .:...:|..|..|:..:|||.         .|....|.|.|.:     ...|.:.|...::.||:
Mouse   125 WMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAF 189

  Fly   283 MVS 285
            ..|
Mouse   190 FAS 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	29/158 (18%)
Bcl2l2	NP_031563.1	BH4	9..29		4/17 (24%)
		bcl-2	11..193	CDD:273308	38/198 (19%)
		BH1	85..104		5/18 (28%)
		BH2	136..151		4/14 (29%)