DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Debcl and Bcl2l1

DIOPT Version :9

Sequence 1:	NP_788278.1	Gene:	Debcl / 53585	FlyBaseID:	FBgn0029131	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001276668.1	Gene:	Bcl2l1 / 12048	MGIID:	88139	Length:	235	Species:	Mus musculus

Alignment Length:	125	Identity:	35/125 - (28%)
Similarity:	58/125 - (46%)	Gaps:	22/125 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 EVFP------ALNSMGEELERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSIT 199
            ||.|      ||...|:|.|..:.|.:::::.||...|       ..|......|..:|||..:.
Mouse    79 EVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITP-------GTAYQSFEQVVNELFRDGVN 136

  Fly   200 WGKIISIFAVCGGFAIDCVRQGHFDYLQCLIDGLAE----IIEDDLVYWLIDNGGWLGLS 255
            ||:|::.|:..|...::.|.:    .:|.|:..:|.    .:.|.|..|:.:|||| |:|
Mouse   137 WGRIVAFFSFGGALCVESVDK----EMQVLVSRIASWMATYLNDHLEPWIQENGGW-GVS 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	35/125 (28%)
Bcl2l1	NP_001276668.1	bcl-2	1..>188	CDD:273308	31/119 (26%)
		BH4	1..27	CDD:128561
		BH4	4..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..73
		Bcl-2_like	<81..188	CDD:132900	29/117 (25%)
		BH3	86..100		5/13 (38%)
		BH1	129..148		7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4728
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810