Protein Alignment Debcl and Bcl2

DIOPT Version :10

• Sequence 1: NP_788278.1
• Gene: Debcl / 53585
• FlyBaseID: FBgn0029131
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_033871.2
• Gene: Bcl2 / 12043
• MGIID: 88138
• Length: 236
• Species: Mus musculus
• Alignment Length: 279
• Identity: 63/279 - (22%)
• Similarity: 91/279 - (32%)
• Gaps: 85/279 - (30%)

  Fly    24 YTANRRGTIATASSDWKALRGGVGGGAGGP-GSVPNPSNGRSLHAGGPM-----TRAASTSSLAS 82
            |..::||      .:|.|     |.....| |:.|.|..........||     ..||.||.|
Mouse    21 YKLSQRG------YEWDA-----GDADAAPLGAAPTPGIFSFQPESNPMPAVHRDMAARTSPL-- 72

  Fly    83 STRTMTNYQEYKMDIINQGKCLCGQYIRARLRRAGVLNRKVTQRLRNILDPGSSHVVYEVFPALN 147
                                       |..:..||               |..|.|...|...|.
Mouse    73 ---------------------------RPLVATAG---------------PALSPVPPVVHLTLR 95

  Fly   148 SMGEELERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSITWGKIISIFAVCGG 212
            ..|::..|.:.|.:..:|.||...||       .|......|.::|||..:.||:|::.|...|.
Mouse    96 RAGDDFSRRYRRDFAEMSSQLHLTPF-------TARGRFATVVEELFRDGVNWGRIVAFFEFGGV 153

  Fly   213 FAIDCVRQGHFDYLQCLIDGLA----EIIEDDLVYWLIDNGGWLGLSRHIRPRVGEFTFLGWLTL 273
            ..::.|.:    .:..|:|.:|    |.:...|..|:.|||||........|.:.......||:|
Mouse   154 MCVESVNR----EMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSL 214

  Fly   274 FVTIS---------AGAYM 283
            ...:|         .|||:
Mouse   215 KTLLSLALVGACITLGAYL 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	38/153 (25%)
Bcl2	NP_033871.2	BH4	10..30		3/14 (21%)
		bcl-2	11..236	CDD:273308	63/279 (23%)
		BH3	90..104		3/13 (23%)
		BH1	133..152		7/18 (39%)
		BH2	184..199		6/14 (43%)