DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Debcl and Bak1

DIOPT Version :9

Sequence 1:	NP_788278.1	Gene:	Debcl / 53585	FlyBaseID:	FBgn0029131	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_031549.2	Gene:	Bak1 / 12018	MGIID:	1097161	Length:	209	Species:	Mus musculus

Alignment Length:	160	Identity:	36/160 - (22%)
Similarity:	70/160 - (43%)	Gaps:	15/160 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 LDPGSSHVVYEVFPALNSMGEELERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFR 195
            |:|.|  ::.:|...|..:|:::.|.:...:.|:..||........|       |...:|..||:
Mouse    63 LEPNS--ILGQVGRQLALIGDDINRRYDTEFQNLLEQLQPTAGNAYE-------LFTKIASSLFK 118

  Fly   196 SSITWGKIISIFAVCGGFAIDCVRQGHFDYLQCLIDGLAEII-EDDLVYWLIDNGGWLGLSRHIR 259
            |.|:||:::::.......|:...::|...:|..:...||:|| ...:..|:...|||:......|
Mouse   119 SGISWGRVVALLGFGYRLALYVYQRGLTGFLGQVTCFLADIILHHYIARWIAQRGGWVAALNFRR 183

  Fly   260 PRVGEFTFLGWLTLFVTISAGAYMVSNVCR 289
            ..:     |..:.:|..:..|.::|....|
Mouse   184 DPI-----LTVMVIFGVVLLGQFVVHRFFR 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	30/126 (24%)
Bak1	NP_031549.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28
		Bcl-2_like	27..181	CDD:132900	30/126 (24%)
		BH3	72..86		3/13 (23%)
		BH1	115..134		6/18 (33%)
		BH2	167..182		4/14 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4728
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810