Protein Alignment Debcl and mcl1

DIOPT Version :10

• Sequence 1: NP_788278.1
• Gene: Debcl / 53585
• FlyBaseID: FBgn0029131
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: XP_002935512.1
• Gene: mcl1 / 100038211
• XenbaseID: XB-GENE-487620
• Length: 283
• Species: Xenopus tropicalis
• Alignment Length: 271
• Identity: 56/271 - (20%)
• Similarity: 100/271 - (36%)
• Gaps: 68/271 - (25%)

  Fly    27 NRRGTIATASSDWKALRGGVGGGAGGPGSVPN----PSNGRSLHAGGPMTRAASTSSLASSTRTM 87
            |..|:: |||.:.: |...:.||:.|..|.|:    |.:|.
 Frog    67 NSGGSL-TASQEGE-LDEDIDGGSQGSSSPPDSPVCPKDGL------------------------ 105

  Fly    88 TNYQEYKMDIINQGKCLCGQYIRARLRRAGVLNRKVTQRLRNILDPGSSHVVYEVFPALNSMGEE 152
              |.:.:..|:...:..||:      ..:|:   |.:..|.:...|       :....|..:|.:
 Frog   106 --YMDTQQLILAFFRGYCGE------ETSGL---KASFLLHHGAHP-------KALETLQRVGGD 152

  Fly   153 LERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSIT-WGKIISIFAVCGGFAID 216
            :...|...:|.:.::||.....:|:.....|.|       :|...:| ||:|:::.:. |.|...
 Frog   153 IIEKHHMAFTGMLQRLSIHSREDLQKLSEVPAL-------VFNDGVTNWGRIVTVISF-GAFVAK 209

  Fly   217 CVRQGHFDYLQCLIDGLAE----IIEDDLVYWLIDNGGWLGLSR--HIRP-RVGEFTFLGWLTLF 274
            .::.  .|...|:: .|||    .:......|:|...||.|...  ||.. ..|..|.|...:..
 Frog   210 HLKS--IDLEDCIM-ALAEHFTLFLMTSKKDWIIQEKGWEGFVDFFHIEDYESGLRTVLMAFSSV 271

  Fly   275 VTISAG-AYMV 284
            ..:.|| |:|:
 Frog   272 AVLGAGLAFMI 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Debcl	NP_788278.1	Bcl-2_like	107..257	CDD:132900	30/156 (19%)
mcl1	XP_002935512.1	Bcl-2_like	106..251	CDD:132900	34/171 (20%)