Protein Alignment Ugt37B1 and Ugt1a6a

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 544
• Identity: 160/544 - (29%)
• Similarity: 264/544 - (48%)
• Gaps: 72/544 - (13%)

  Fly    22 ANILG---LFTSLSPSHLVIQMSMARILAERGHNVTV----VTILKPPSLH--KDINHILVPMEE 77
            |::||   |......||.:....:...|:||||::.|    |.:|...|.:  :.|..:...:||
Mouse    22 ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIMVLVPEVNLLLGESKYYRRKIFSVTYSLEE 86

  Fly    78 DILQ----AFN--------SVVGGMTKTDNSNAYVSMFRSVRQLSETFSKMGDVMKQPLVKD--- 127
              ||    .|.        |::|.:.:..|:...|.||         ||..     |.|:||
Mouse    87 --LQTRFRTFGNNHFLPGASLMGPLREYRNNMIVVDMF---------FSNC-----QSLLKDSAT 135

  Fly   128 LYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLG-NPWEVSYVPGMSVSI 191
            |....:||||.:.....|.| .:.||..|.:|.|......|..|.::|| :|..|||||....
Mouse   136 LSFLRENKFDALFTDPAMPC-GVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYT-- 197

  Fly   192 KGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFFASHG 256
            |....:.|..|:.|.:.::.:....:.:..:...|..::...|.:|||   ||:| ||.......
Mouse   198 KFSDHMTFPQRLANFIVNILENYLYYCLYSKYEIIASDLLKRDVSLPS---LHQN-SLWLLRYDF 258

  Fly   257 ISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQK 320
            :.|.| ||.:|.:|.:|||..|:: .:|.|..|.:: :...:|.::.||||.:.|  :......:
Mouse   259 VFEYP-RPVMPNMIFLGGINCKKK-GKLTQEFEAYVNASGEHGIVVFSLGSMVSE--IPEKKAME 319

  Fly   321 MFNVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQY 383
            :...|.::.|.|:|::...  .|:   ::|.:..||:||.|:|.||....||||:|..|:.|...
Mouse   320 IAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGIC 381

  Fly   384 HGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYR 448
            :|.||:.:|:||||..||..|...|.|:..::|.:..|.....::.|::|..|...:...|:|::
Mouse   382 NGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHK 446

  Fly   449 DRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVILGTIVALCFIT------ 506
            |||:.|.:..::|||||:|:.||||:: |..| :::...::|||...:|..::.:.||.
Mouse   447 DRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAY 510

  Fly   507 --KLLFGLVVGKLR-KNSRKAKVN 527
              :..||   ||.| |.|.|:|.:
Mouse   511 GCRKCFG---GKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	158/538 (29%)
		egt	13..483	CDD:223071	145/489 (30%)
Ugt1a6a	NP_659545.2	egt	15..503	CDD:223071	149/511 (29%)
		UDPGT	27..522	CDD:278624	152/528 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840725
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840