DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37B1 and UGT74E2

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_172059.1	Gene:	UGT74E2 / 837075	AraportID:	AT1G05680	Length:	453	Species:	Arabidopsis thaliana

Alignment Length:	476	Identity:	103/476 - (21%)
Similarity:	167/476 - (35%)	Gaps:	151/476 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 HLVIQMSMARILAERGHNVTVVTILKPPS-----LH-------------------KDINHILVPM 75
            |:.......:.||.:|..:|:|.:...||     .|                   :|::..:..:
plant    17 HITPMSQFCKRLASKGLKLTLVLVSDKPSPPYKTEHDSITVFPISNGFQEGEEPLQDLDDYMERV 81

  Fly    76 EEDILQAFNSVVGGMTKTDN---SNAYVSMFRSVRQLSETFSKMGDV-MKQP-LVKDLYEH---- 131
            |..|......:|..|..:.|   :..|.|....:..::.::...|.| ..|| ||..:|.|
plant    82 ETSIKNTLPKLVEDMKLSGNPPRAIVYDSTMPWLLDVAHSYGLSGAVFFTQPWLVTAIYYHVFKG 146

  Fly   132 ----PDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGNPWEVSYVPGM----- 187
                |..|:.           ...||.....|::.| ::.||||       .|.|..|.:
plant   147 SFSVPSTKYG-----------HSTLASFPSFPMLTA-NDLPSFL-------CESSSYPNILRIVV 192

  Fly   188 -------SVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSY----- 240
                   .|.|.          :.|....:.::|..::..|      ..:....||:||.
plant   193 DQLSNIDRVDIV----------LCNTFDKLEEKLLKWVQSL------WPVLNIGPTVPSMYLDKR 241

  Fly   241 --EDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFLSEAPNGAILLS 303
              ||  ||.....|.:                            ::.:.||...|:.||..:.||
plant   242 LSED--KNYGFSLFNA----------------------------KVAECMEWLNSKEPNSVVYLS 276

  Fly   304 LGS--NLKEDHLKSSTVQKMFNVLSKLQQK---VIW--KWDDLDNIPGE-----SENILYSKWVP 356
            .||  .||||        :|..:.:.|:|.   .:|  :..:...:|..     .|..|...|.|
plant   277 FGSLVILKED--------QMLELAAGLKQSGRFFLWVVRETETHKLPRNYVEEIGEKGLIVSWSP 333

  Fly   357 QVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMV-MHGFGIKQSILTLEE 420
            |:|||||.:|..|:||.|.....|....|.||:.:|.:.|||:||..|. :...|::   :..|.
plant   334 QLDVLAHKSIGCFLTHCGWNSTLEGLSLGVPMIGMPHWTDQPTNAKFMQDVWKVGVR---VKAEG 395

  Fly   421 DSF------LQGIREVLDNPK 435
            |.|      ::.:.||::..|
plant   396 DGFVRREEIMRSVEEVMEGEK 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	103/476 (22%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	103/476 (22%)
UGT74E2	NP_172059.1	Glycosyltransferase_GTB-type	6..450	CDD:415824	103/476 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000