DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37B1 and UGT76E1

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_200766.2	Gene:	UGT76E1 / 836077	AraportID:	AT5G59580	Length:	453	Species:	Arabidopsis thaliana

Alignment Length:	520	Identity:	106/520 - (20%)
Similarity:	186/520 - (35%)	Gaps:	160/520 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVV-TILKPPSLHK 66
            |:.|    :||::...|.|             |:...|.:.:.|..:|.::||| |.....|..|
plant     5 GVKR----RIVLVPVPAQG-------------HVTPIMQLGKALYSKGFSITVVLTQYNRVSSSK 52

  Fly    67 DIN--HILVPMEEDILQAFNSVVGGMTKTD--NSNAYVSMFRSVRQLSETFSKMGDVMKQPLVKD 127
            |.:  |.|            ::.|.:|::|  |...:..:|: :.|:.|...|.       .:..
plant    53 DFSDFHFL------------TIPGSLTESDLKNLGPFKFLFK-LNQICEASFKQ-------CIGQ 97

  Fly   128 LYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVV-------------ALS--NPPSFLGYLLGN 177
            |.:...|....|:...:|...|.|: .:.::|.|:             .||  |..|||..:...
plant    98 LLQEQGNDIACVVYDEYMYFSQAAV-KEFQLPSVLFSTTSATAFVCRSVLSRVNAESFLLDMKDP 161

  Fly   178 PWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQ--RLFMFIIELRNARIYREIYGDDPTL--P 238
            .......||:       .||.:.....:..|.:..  :::...:.:|.|...  |......|  .
plant   162 KVSDKEFPGL-------HPLRYKDLPTSAFGPLESILKVYSETVNIRTASAV--IINSTSCLESS 217

  Fly   239 SYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQV-KEQPERL---PQNMEQFLSEAPNGA 299
            |...|.|.:.:           |:.|       ||.:.: ...|..|   .::..::|::...|:
plant   218 SLAWLQKQLQV-----------PVYP-------IGPLHIAASAPSSLLEEDRSCLEWLNKQKIGS 264

  Fly   300 IL-LSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIW----------KWDDLDNIPGE-----SEN 348
            :: :||||...   :::..:.:|...|....|..:|          :|  .:::|.|     ||.
plant   265 VIYISLGSLAL---METKDMLEMAWGLRNSNQPFLWVIRPGSIPGSEW--TESLPEEFSRLVSER 324

  Fly   349 ILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNAD----------- 402
            ....||.||::||.||.:..|.:|.|.....|:...|.||:..|..|||..||.
plant   325 GYIVKWAPQIEVLRHPAVGGFWSHCGWNSTLESIGEGVPMICRPFTGDQKVNARYLERVWRIGVQ 389

  Fly   403 -----------------VMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVK----SFSTL 446
                             :|...|..:::.::.|:|              |...:||    |||:|
plant   390 LEGELDKGTVERAVERLIMDEEGAEMRKRVINLKE--------------KLQASVKSRGSSFSSL 440

Fly 447 446
plant 441 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	104/511 (20%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	103/510 (20%)
UGT76E1	NP_200766.2	Glycosyltransferase_GTB_type	1..450	CDD:299143	106/520 (20%)
UGT76E1	NP_200766.2	YjiC	7..429	CDD:224732	99/505 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000