DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37B1 and UGT76B1

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_187742.1	Gene:	UGT76B1 / 820307	AraportID:	AT3G11340	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	113/526 - (21%)
Similarity:	180/526 - (34%)	Gaps:	148/526 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLHKDINHILVPMEEDILQ-AFNSVV 87
            ::.||......||.....:|.|...||.::||:        |.:.|.   |...:... .|.|:.
plant     9 VIFLFPFPLQGHLNPMFQLANIFFNRGFSITVI--------HTEFNS---PNSSNFPHFTFVSIP 62

  Fly    88 GGMTKTDNSNAYVSMFRSVRQL-SETFSKMGDVMKQPLVKDLYEHPDNKFDLV-MVGYFMNCYQL 150
            ..:::.:   :|..:...:..| |:..:..||.:|    |.:.|.|.....:| .:.||.:
plant    63 DSLSEPE---SYPDVIEILHDLNSKCVAPFGDCLK----KLISEEPTAACVIVDALWYFTH---- 116

  Fly   151 ALAHKLKVP-LVVALSNPPSFL-----------GYL-------------------LGNPWEVSYV 184
            .|..|...| :|:...|..:|:           |||                   ...||..:..
plant   117 DLTEKFNFPRIVLRTVNLSAFVAFSKFHVLREKGYLSLQETKADSPVPELPYLRMKDLPWFQTED 181

  Fly   185 PGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISL 249
            |      :.|..|..|  |:..|.|.:..:|..|.:|...::      |:             :.
plant   182 P------RSGDKLQIG--VMKSLKSSSGIIFNAIEDLETDQL------DE-------------AR 219

  Fly   250 IFFASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNME--QFL-SEAPNGAILLSLGSNLKED 311
            |.|.......||....|.|          .....|..:|.  .:| .:|.|..|..||||....|
plant   220 IEFPVPLFCIGPFHRYVSA----------SSSSLLAHDMTCLSWLDKQATNSVIYASLGSIASID 274

  Fly   312 HLKSSTVQKMFNVLSKLQQKVIW----------KWDD------LDNIPGESENILYSKWVPQVDV 360
              :|..::..:. |....|..:|          :|.:      ::|:.|..:.:   ||.||.:|
plant   275 --ESEFLEIAWG-LRNSNQPFLWVVRPGLIHGKEWIEILPKGFIENLEGRGKIV---KWAPQPEV 333

  Fly   361 LAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNA----DVMVMHGFGIKQSILTLEED 421
            |||.....|:||.|.....|......||:..|.||||..||    ||..: |..::..:..|
plant   334 LAHRATGGFLTHCGWNSTLEGICEAIPMICRPSFGDQRVNARYINDVWKI-GLHLENKVERL--- 394

  Fly   422 SFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAA 486
                    |::|........|.....|.|.:..:||    ||..::..|:          |:...
plant   395 --------VIENAVRTLMTSSEGEEIRKRIMPMKET----VEQCLKLGGS----------SFRNL 437

  Fly   487 NNLDVY 492
            .||..|
plant   438 ENLIAY 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	113/526 (21%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	109/515 (21%)
UGT76B1	NP_187742.1	Glycosyltransferase_GTB-type	1..444	CDD:415824	113/526 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000