DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37B1 and UGT74D1

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001325305.1	Gene:	UGT74D1 / 817732	AraportID:	AT2G31750	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	113/505 - (22%)
Similarity:	179/505 - (35%)	Gaps:	175/505 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLHKDINHILVPMEEDILQAFNSV 86
            ||:| :|:.....|:...:..::.|..:..|||.:|   ..|.|..|..             .::
plant     7 ANVL-VFSFPIQGHINPLLQFSKRLLSKNVNVTFLT---TSSTHNSILR-------------RAI 54

  Fly    87 VGGMT------------------KTDNSNAYVSMFRS--VRQLSETFSKMGDVMKQPLVKDLYEH 131
            .||.|                  .||.|..|.:.|:.  .|.|||..|.|
plant    55 TGGATALPLSFVPIDDGFEEDHPSTDTSPDYFAKFQENVSRSLSELISSM--------------- 104

  Fly   132 PDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALS--------NPPSFLGYLLGNPWEVS---YVP 185
             |.|.:.|:   :.:|....|....|.|.|.|.|        | .:::.:|.|...|..   .:|
plant   105 -DPKPNAVV---YDSCLPYVLDVCRKHPGVAAASFFTQSSTVN-ATYIHFLRGEFKEFQNDVVLP 164

  Fly   186 GMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHK---NI 247
            .|. .:||..                  |.:|            :|.::...|.:|.:..   |:
plant   165 AMP-PLKGND------------------LPVF------------LYDNNLCRPLFELISSQFVNV 198

  Fly   248 SLI-FFASHGISE------------GPIR---PNVPAV-------------IEIGGIQVKEQPER 283
            ..| ||..:...|            .|::   |.:|::             |.:...||.|..:.
plant   199 DDIDFFLVNSFDELEVEVLQWMKNQWPVKNIGPMIPSMYLDKRLAGDKDYGINLFNAQVNECLDW 263

  Fly   284 LPQNMEQFLSEAPNGAILLSLGS--NLKEDHLKSSTVQKMFNVLSKLQQ---KVIW--KWDDLDN 341
            |.       |:.|...|.:|.||  .||:|        :|..|.:.|:|   ..:|  :..:...
plant   264 LD-------SKPPGSVIYVSFGSLAVLKDD--------QMIEVAAGLKQTGHNFLWVVRETETKK 313

  Fly   342 IPGE-SENI----LYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNA 401
            :|.. .|:|    |...|.||:.||||.:|..|:||.|.....||...|..::.:|.:.|||:||
plant   314 LPSNYIEDICDKGLIVNWSPQLQVLAHKSIGCFMTHCGWNSTLEALSLGVALIGMPAYSDQPTNA 378

  Fly   402 ----DVMVM--------HGFGIKQSIL----TLEEDSFLQGIREVLDNPK 435
                ||..:        :||..|:.|:    .:.||...:| :|:..|.:
plant   379 KFIEDVWKVGVRVKADQNGFVPKEEIVRCVGEVMEDMSEKG-KEIRKNAR 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	113/505 (22%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	113/505 (22%)
UGT74D1	NP_001325305.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000