DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37B1 and UGT71C2

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_180535.1	Gene:	UGT71C2 / 817524	AraportID:	AT2G29740	Length:	474	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	104/468 - (22%)
Similarity:	180/468 - (38%)	Gaps:	108/468 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PSHLVIQMSMA-RILAERGHNVTVVTILKPPSLHKDINHILVPM--EEDILQAFNSVVGG----- 89
            |.|::..:.:| |:::.:...:..:|||          |..:|.  :.|.:....|::..
plant    17 PGHILATIELAKRLISHQPSRIHTITIL----------HWSLPFLPQSDTIAFLKSLIETESRIR 71

  Fly    90 -MTKTDNSN-AYVSMF--RSVRQLSETFSKMGDVMKQPLVKD----LYEHPDNKFDLVMVGYFMN 146
             :|..|..| ..:.:|  .|...:.|...||     .|||::    |....|....:.:.|..::
plant    72 LITLPDVQNPPPMELFVKASESYILEYVKKM-----VPLVRNALSTLLSSRDESDSVHVAGLVLD 131

  Fly   147 CYQLAL---AHKLKVPLVVALSNPPSFLG---YLL------------GNPWEVSYVPGM--SVSI 191
            .:.:.|   .::..:|..:.|:...||||   |||            .:..|...|||.  ||.:
plant   132 FFCVPLIDVGNEFNLPSYIFLTCSASFLGMMKYLLERNRETKPELNRSSDEETISVPGFVNSVPV 196

  Fly   192 KGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFFASHG 256
            |...|..|..........||:|             :.|..|  ..:.|:|.|.:| :..:|..
plant   197 KVLPPGLFTTESYEAWVEMAER-------------FPEAKG--ILVNSFESLERN-AFDYFDR-- 243

  Fly   257 ISEGPIRP-NVPAVIEIGGIQVKEQPERLP----QNMEQFLSEAPNGAILLSLGSNLKEDHLKSS 316
                  || |.|.|..||.|........|.    ..:.::|.:.|..:::.....:||.  |.:|
plant   244 ------RPDNYPPVYPIGPILCSNDRPNLDLSERDRILKWLDDQPESSVVFLCFGSLKS--LAAS 300

  Fly   317 TVQKMFNVLSKLQQKVIWKWDDLDNIPGE--SENI--------------LYSKWVPQVDVLAHPN 365
            .::::...|..:..:.:|   .:...|.|  |.|.              |...|.|||::|||..
plant   301 QIKEIAQALELVGIRFLW---SIRTDPKEYASPNEILPDGFMNRVMGLGLVCGWAPQVEILAHKA 362

  Fly   366 ITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLE-EDSFLQGIRE 429
            |..|::|.|...:.|:...|.|:...|::.:|..||..:|      |:..|.|| ...::....|
plant   363 IGGFVSHCGWNSILESLRFGVPIATWPMYAEQQLNAFTIV------KELGLALEMRLDYVSEYGE 421

  Fly   430 VLDNPKYATAVKS 442
            ::...:.|.||:|
plant   422 IVKADEIAGAVRS 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	104/468 (22%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	104/468 (22%)
UGT71C2	NP_180535.1	PLN02167	4..474	CDD:215112	104/468 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000