DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37B1 and UGT84B2

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_179906.1	Gene:	UGT84B2 / 816857	AraportID:	AT2G23250	Length:	438	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	102/522 - (19%)
Similarity:	176/522 - (33%)	Gaps:	163/522 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 HLVIQMSMARILAERGHNVTVVTILKPPSL--------HKDINHILVPMEEDILQAFNSVVGGMT 91
            ||...:..|:.||....:.|:.|..:...|        |:.::           .||.|  .|:.
plant     9 HLNPMLKFAKHLARTNLHFTLATTEQARDLLSSTADEPHRPVD-----------LAFFS--DGLP 60

  Fly    92 KTDNSNAYVSMFRSVRQLSETFSKMGDVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKL 156
            |.|.        |....|:::..|.|......:::      :.:||.:          :::....
plant    61 KDDP--------RDPDTLAKSLKKDGAKNLSKIIE------EKRFDCI----------ISVPFTP 101

  Fly   157 KVPLVVALSNPPS--------------FLGYLLGNPW------------------EVSYVPGMSV 189
            .||.|.|..|.|.              :..|:..||:                  ||..:|.:.:
plant   102 WVPAVAAAHNIPCAILWIQACGAFSVYYRYYMKTNPFPDLEDLNQTVELPALPLLEVRDLPSLML 166

  Fly   190 SIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFFAS 254
            ..:|.       .|..|:...|..|......|.|:  :.|:  :...:.|..||...|
plant   167 PSQGA-------NVNTLMAEFADCLKDVKWVLVNS--FYEL--ESEIIESMSDLKPII------- 213

  Fly   255 HGISEGPIRPNVPAVIEIGGIQVKEQPERLPQN--MEQFLSEAPNGAILLSLGSNLKEDHLKSST 317
                  ||.|.|...: :|..:.|........:  ||....:|.:..:.:|.||.||      |.
plant   214 ------PIGPLVSPFL-LGNDEEKTLDMWKVDDYCMEWLDKQARSSVVYISFGSILK------SL 265

  Fly   318 VQKMFNVLSKLQQK-VIWKWDDLDNIPGESENIL----------YSKWVPQVDVLAHPNITLFIT 371
            ..::..:.:.|:.: |.:.|.......||:..:|          .::|..|..:|:|..|:.|||
plant   266 ENQVETIATALKNRGVPFLWVIRPKEKGENVQVLQEMVKEGKGVVTEWGQQEKILSHMAISCFIT 330

  Fly   372 HAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMV-MHGFGIKQ-------SILTLEEDSFLQGIR 428
            |.|.....|....|.|::|.|.:.|||.:|.::| :.|.|::.       .:...|.:..::.:.
plant   331 HCGWNSTIETVVTGVPVVAYPTWIDQPLDARLLVDVFGIGVRMKNDAIDGELKVAEVERCIEAVT 395

  Fly   429 E---VLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLD 490
            |   ..|..:.||.:|                           |.|....||    ...:|.|||
plant   396 EGPAAADMRRRATELK---------------------------HAARSAMSP----GGSSAQNLD 429

  Fly   491 VY 492
            .:
plant   430 SF 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	102/522 (20%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	98/511 (19%)
UGT84B2	NP_179906.1	PLN02210	1..438	CDD:215127	102/522 (20%)
UGT84B2	NP_179906.1	YjiC	8..420	CDD:224732	96/505 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000