Protein Alignment Ugt37B1 and ugt1b4

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001166239.2
• Gene: ugt1b4 / 795050
• ZFINID: ZDB-GENE-080227-13
• Length: 533
• Species: Danio rerio
• Alignment Length: 561
• Identity: 145/561 - (25%)
• Similarity: 251/561 - (44%)
• Gaps: 113/561 - (20%)

  Fly     3 GISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQM---------SMARILAERGHNVTVV-- 56
            |:..||   :|.::..|.....|...:|.:...||:.|         ::|..:..|||.|.||
Zfish     8 GVIICL---VVGVVCSAVVDQKLSRNSSWTGKLLVVPMDGSHWTGVKAVAEEMGRRGHTVIVVIP 69

  Fly    57 --TILKPPSLHKDINHILVPMEEDIL-QAFNSVVGGMTKTDNSNAYVSMFRSVRQLSETFSKMGD 118
              ::...|..|.......|..::|:: |.....|..:..::.     |:.::|..:...|.|:.|
Zfish    70 EISMRLGPGKHYITKKFPVQYKQDLINQIMVEHVNEVAASEQ-----SLLKTVTSIMYRFGKIID 129

  Fly   119 ---------VMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLV------------V 162
                     ..:|.|::.|   .|..||.|:....|....: ||:.|.||.|            .
Zfish   130 HFISTSESLFQEQELIEFL---RDQNFDAVLTNPAMPMGAI-LAYNLSVPAVYMLRGIMCESKAT 190

  Fly   163 ALSNPPSFLGYLLGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIY 227
            |..|||             ||:|.....|  ...:.|..||:|.|.|:.:.|...::
Zfish   191 ACPNPP-------------SYIPRFFTQI--SDRMTFSERVINTLVSLLEPLMCRLM-------- 232

  Fly   228 REIYGDDPTLPSYED-----LHKNISL--------IFFASHGIS-EGPIRPNVPAVIEIGGIQVK 278
                     |.|:|:     ||:::|:        ::...:..: |.| :|.:|.:|.||||..
Zfish   233 ---------LGSFEEMTSKFLHRDVSITEILSTAAVWLMRYDFTLEFP-KPLMPNMITIGGINC- 286

  Fly   279 EQPERLPQNMEQFLS-EAPNGAILLSLGSNLKEDHLKSSTVQK----MFNVLSKLQQKVIWKW-- 336
            |....|.:.:|:|:: ...:|.::.||||      |.||..::    .|...|.:.|:|:|::
Zfish   287 EVKNPLTKEVEEFVNGSGEHGIVVFSLGS------LVSSMPKEKADIFFKAFSMIPQRVLWRYTG 345

  Fly   337 DDLDNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNA 401
            :..:|:|   ||:...||:||.|:|.||....||||.|..|:.|...||.||:.||:||||..|.
Zfish   346 EIPNNVP---ENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNV 407

  Fly   402 DVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVI 466
            ..:...|.|:..||..:..::.|..:..|::|..|...::..|.::.|||:.|.:..::|.|:|:
Zfish   408 HRVATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVM 472

  Fly   467 RYHGAPHIQSPVVHMSYIAANNLDV--YAVILGTIVALCFI 505
            |:.||.|::.....::::..::|||  :.:::..||.|..:
Zfish   473 RHKGADHLRPAAHELNWLQYHSLDVIGFMLLIVLIVTLAML 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	127/494 (26%)
ugt1b4	NP_001166239.2	UDPGT	35..529	CDD:278624	138/531 (26%)