Protein Alignment Ugt37B1 and ugt5c2

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001038851.1
• Gene: ugt5c2 / 751669
• ZFINID: ZDB-GENE-060825-206
• Length: 552
• Species: Danio rerio
• Alignment Length: 545
• Identity: 153/545 - (28%)
• Similarity: 257/545 - (47%)
• Gaps: 97/545 - (17%)

  Fly    13 VVLIAGA--HGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVT-----ILKPPSLHKDINH 70
            |:.|.|:  .|..|  |...|..||.|....:.:.|..:||.|.|:.     .:|..|.:.|.
Zfish    38 VITIFGSLCDGGKI--LVAPLEGSHWVNMDILIKALHGQGHTVDVIRNANSWFIKENSTYYDT-- 98

  Fly    71 ILVP----MEEDILQAFNSVVGGMTKTDNSNA--------YVSMFRSVRQLSETFSKM--GDVMK 121
            |.:|    .:|:....|   |..|.|.:....        |:::|.:|::..|...::  ..:..
Zfish    99 ITIPNTKGWDEEFAADF---VYKMIKYEKEKGSWLSIVRLYLNVFDAVKKTHEMVCQLITNILDS 160

  Fly   122 QPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGNPWEVSYVPG 186
            :.::|.|.|   .::||::....... .:.||||||:|:|..:....:..|:....|..:||:|
Zfish   161 EEILKMLNE---KQYDLMLTDPVWGT-GIILAHKLKLPMVYNVRWTTTGEGHFDIAPSPMSYIP- 220

  Fly   187 MSVSIKGGKPLGFGHRVLNLLGSMAQRL----FMFIIELR----NARIYREIYGDDPTLPSYEDL 243
                |.|.   |...|:     |..|||    |..:::|:    |.:.|:.|.  |....|..:.
Zfish   221 ----ITGS---GNTDRM-----SFFQRLKNYFFYLLLDLQLSHFNVKQYQAIC--DKYFTSRVNF 271

  Fly   244 HK----------NISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPER-LPQNMEQFL-SEAP 296
            |:          .:..:|       |.| ||.:|.:|.|||.|.  .|.: ||.::|.|: |...
Zfish   272 HELLQGADLWLMRVDFVF-------EFP-RPTMPNIIYIGGFQC--PPAKPLPHDLEDFMQSSGD 326

  Fly   297 NGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDLDNIPGE-----SENILYSKWVP 356
            :|.|::||||.:  .:|..:...::....::|.|||||::      .|:     |.|.|...|:|
Zfish   327 HGVIVMSLGSLI--GNLPENVTAEIAAAFARLPQKVIWRY------TGKKPSTLSNNTLMVDWMP 383

  Fly   357 QVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEED 421
            |.|:|.||...:||:|.|..|:.||.|||.|::.:|.|.||..|...:...|.....||..|.|:
Zfish   384 QKDLLGHPKTKVFISHGGTNGVLEALYHGVPVIGIPFFFDQYDNLIRLQARGGAKLLSIADLGEN 448

  Fly   422 SFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAA 486
            :....|:||::.|.|...:...|.|::|:|:.|.::.|:|:|:|:|:.||.|:::....|.:.:.
Zfish   449 TLHAAIQEVINEPSYRLNMHKLSHLHKDKPVKPLDSAIFWIEFVMRHKGAAHLRTESYKMPWYSY 513

  Fly   487 NNLDV----YAVILGTIVALC-FIT 506
            :::||    :||:|  |:..| |:|
Zfish   514 HSVDVVVTLFAVVL--ILTYCIFVT 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	132/482 (27%)
ugt5c2	NP_001038851.1	UDPGT	49..551	CDD:278624	149/534 (28%)