Protein Alignment Ugt37B1 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 517
• Identity: 142/517 - (27%)
• Similarity: 238/517 - (46%)
• Gaps: 72/517 - (13%)

  Fly    46 LAERGHNVTVV----TILKPPSLHKDINHILVPMEEDILQAFNSVVGGMTKTDNSNAYVSMFRS- 105
            |.:|||.|||:    :||..|:....:...:.|.             .:|||:..|..:...:.
Human    46 LIQRGHEVTVLASSASILFDPNNSSALKIEIYPT-------------SLTKTELENFIMQQIKRW 97

  Fly   106 -----------VRQLSETFSKMGDVMKQPLVKDLYEH-------PDNKFDLVMVGYFMNCYQLAL 152
                       ..|:.|..|..||:.:: ..||:..:       .:::||::.......|.:| |
Human    98 SDLPKDTFWLYFSQVQEIMSIFGDITRK-FCKDVVSNKKFMKKVQESRFDVIFADAIFPCSEL-L 160

  Fly   153 AHKLKVPLVVALSNPPSFLGYLL-----GNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQ 212
            |....:|.|.:||..|   ||..     |..:..||||.:...:.  ..:.|..||.|::..:..
Human   161 AELFNIPFVYSLSFSP---GYTFEKHSGGFIFPPSYVPVVMSELT--DQMTFMERVKNMIYVLYF 220

  Fly   213 RLFMFIIELRN-ARIYREIYGDDPTLPSYEDLHK-NISLIFFASHGISEGPIRPNVPAVIEIGGI 275
            ..:..|.:::. .:.|.|:.|...||.  |.:.| ::.||..:.:.....|:.|||..|   ||:
Human   221 DFWFEIFDMKKWDQFYSEVLGRPTTLS--ETMGKADVWLIRNSWNFQFPYPLLPNVDFV---GGL 280

  Fly   276 QVKEQPER-LPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQKMFNV----LSKLQQKVIW 334
            ..|  |.: ||:.||.|: |...||.::.||||      :.|:..::..||    |:::.|||:|
Human   281 HCK--PAKPLPKEMEDFVQSSGENGVVVFSLGS------MVSNMTEERANVIASALAQIPQKVLW 337

  Fly   335 KWDDLDNIPGE-SENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQP 398
            ::|  .|.|.. ..|....||:||.|:|.||....||||.|..|:.||.|||.||:.:|:|.|||
Human   338 RFD--GNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQP 400

  Fly   399 SNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVE 463
            .|...|...|..::....|:.....|..::.|:::|.|...|...|.:..|:|:.|.:..::|:|
Human   401 DNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIE 465

  Fly   464 YVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIVALCFITKLLFGLVVGKLRKNSRKAK 525
            :|:|:.||.|::.....:::...::|||...:|..:..:.||..........|..:.::|.|
Human   466 FVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	140/513 (27%)
		egt	13..483	CDD:223071	133/473 (28%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	140/513 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840