Protein Alignment Ugt37B1 and Ugt2a3

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 533
• Identity: 149/533 - (27%)
• Similarity: 253/533 - (47%)
• Gaps: 68/533 - (12%)

  Fly    34 SHLVIQMSMARILAERGHNVTVVTILKPPSLHKD------INHILVPMEEDILQAFNSVVGGMTK 92
            ||.:...::...|..|||.|||   ||.||:..|      ::...:|:..:|..|.|.:......
Mouse    34 SHWLNLKTILEELGARGHEVTV---LKYPSIIIDQSKRIPLHFENIPLLYEIETAENRLNEIANL 95

  Fly    93 TDNSNAYVSMFRSVRQLSETFSKM-GD---VMKQPLV--KDLYEHPDNKFDLVMVGYFMNCYQLA 151
            ..|....:|::.:.:.|.:.|.:: ||   :.:..|.  |.:.:..|.::|:|::...:.|.:|
Mouse    96 AVNVIPNLSLWEAAKTLQDFFLQVTGDFESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGEL- 159

  Fly   152 LAHKLKVPLVVALSNPPSFLGYLLGN-----PWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMA 211
            :|..|::|.|..|.   ..:||.:..     |..:||||.:...:...  :.|..||.|::.|:
Mouse   160 VAEVLQIPFVYTLR---FSMGYYMEKHCGQLPIPLSYVPVVMSELTDN--MTFTERVKNMMFSL- 218

  Fly   212 QRLFMFIIELRNARIYREIYGDD---PT-------------LPSYEDLHKNISLIFFASHGISEG 260
              ||.:.::..:...:.:.|.:.   ||             :.:|.|:               |.
Mouse   219 --LFEYWLQQYDFAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDV---------------EF 266

  Fly   261 PIRPNVPAVIEIGGIQVKEQPER-LPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQKMFN 323
            | ||.:|....:||:..|  |.: ||:.||:|: |...:|.::.||||.:|  :|.......:.:
Mouse   267 P-RPYLPNFEFVGGLHCK--PAKPLPKEMEEFVQSSGEHGVVVFSLGSMVK--NLTEEKANLIAS 326

  Fly   324 VLSKLQQKVIWKWDDLDNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPM 388
            ||:::.|||:|::.........|...|:: |:||.|:|.||....||||.|..|:.||.|||.||
Mouse   327 VLAQIPQKVLWRYSGKKPATLGSNTRLFN-WIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPM 390

  Fly   389 LALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLS 453
            :.:|:.||||.|...|...|..:|.||.|:.....|..:|.|::.|.|.......|.::.|:|:.
Mouse   391 VGVPMLGDQPHNIAHMEAKGAALKVSISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVK 455

  Fly   454 PRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIVALCFITKLLFGLVVGKLR 518
            |.:..::|:|:|:|:.||.|::.....:|:...::|||...:|..:|.|.||.......|..||.
Mouse   456 PLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFIITKFCLFVCQKLY 520

  Fly   519 KNSRKAKVNQKHK 531
            ....|...|:|.|
Mouse   521 MKESKKMGNRKKK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	145/523 (28%)
		egt	13..483	CDD:223071	133/483 (28%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	145/524 (28%)
		egt	<268..507	CDD:223071	83/243 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840