Protein Alignment Ugt37B1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_690024.1
• Gene: Ugt2b1 / 71773
• MGIID: 1919023
• Length: 529
• Species: Mus musculus
• Alignment Length: 514
• Identity: 152/514 - (29%)
• Similarity: 251/514 - (48%)
• Gaps: 81/514 - (15%)

  Fly    34 SHLVIQMSMARILAERGHNVTVV----TILKPPSLHKDINHIL--VPMEEDILQ-AFNSVVGGMT 91
            ||.:....:...|.:|||:|||:    :||..||....||..:  .|:.:|.|: ||...||..|
Mouse    34 SHWINMKIILDELVQRGHDVTVLISSASILIGPSNESSINFEIYSAPLSKDDLEYAFEKWVGNWT 98

  Fly    92 KTDNSNAYVSMFRSVRQLSETFSKMGD------VMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQL 150
            .......:.:.:..::::|..:|.|.:      |..:.|:|.|   ..:|||:|:....:.|.:|
Mouse    99 YELKKLPFWTSYSKLQKISSEYSDMIESFCKAVVWNKSLMKKL---QGSKFDVVLADALVPCGEL 160

  Fly   151 ALAHKLKVPLVVALSNPPSFL--GYLLGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQR 213
             |:..||.|||.:|...|.:.  .|..|.|...||||.:...:  ...:.|..||.|:|..:
Mouse   161 -LSELLKTPLVYSLRFCPGYKCEKYSGGLPLPPSYVPVVLSEL--SDHMTFAERVKNMLQVL--- 219

  Fly   214 LFMFIIELRNARIYREIYGD---DPT-------------LPSYEDL---HKNISLIFFASHGISE 259
            ||.|..:..|.:.:.:.|.|   .||             :.::.||   |
Mouse   220 LFDFWFQTFNEKSWNQFYSDVLGRPTTLTEMMGKADIWLVRTFWDLKFPH--------------- 269

  Fly   260 GPIRPNVPAVIEIGGIQVKEQPER-LPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQKMF 322
             |..||...|   ||:..|  |.: ||:.||:|: |...:|.::.||||.:|  ::|......:.
Mouse   270 -PFLPNFDFV---GGLHCK--PAKPLPKEMEEFVQSSGEHGVVVFSLGSMVK--NIKEEKANVVA 326

  Fly   323 NVLSKLQQKVIWKWDDLDNIPGESENILYS-----KWVPQVDVLAHPNITLFITHAGKGGLTEAQ 382
            :.|:::.|||:|::|      |:..:.|.|     ||:||.|:|.||....||.|.|..|:.||.
Mouse   327 SALAQIPQKVLWRFD------GKKPDTLGSNTRLYKWIPQNDLLGHPKTKAFIAHGGTNGIYEAI 385

  Fly   383 YHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLY 447
            |||.|::.:|:|||||.|.:.:|..|..::....|:.....|..::.|:::|.|.......|.::
Mouse   386 YHGIPIVGIPLFGDQPDNINHIVAKGAAVRVDFDTMSTTDLLTALKTVINDPSYKENAMRLSRIH 450

  Fly   448 RDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVILGTIVALCFI 505
            .|:|:.|.:..::|:|||:|..||.|:: |.:| :::...::|||...:|..:||:.||
Mouse   451 HDQPMKPLDRAVFWIEYVMRNKGAKHLR-PALHDLTWFQYHSLDVIGFLLVCVVAVVFI 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	134/467 (29%)
Ugt2b1	NP_690024.1	UDPGT	24..527	CDD:278624	152/514 (30%)