Protein Alignment Ugt37B1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 557
• Identity: 155/557 - (27%)
• Similarity: 247/557 - (44%)
• Gaps: 73/557 - (13%)

  Fly     8 LALQIVVLIA-GAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLHKDINHI 71
            |.|::.:|:| |...|..| |...:..||......:...|:.|||.|.||.......|.|..|..
Mouse    10 LPLRVCLLLAFGLAQAGRL-LVVPMDGSHWFSMKMIVEKLSHRGHEVVVVIPEVSWHLGKSQNFT 73

  Fly    72 LVPME-----EDILQAFNSVVGGMTKTDNSNAYVSMFRSVRQLSETF--------------SKMG 117
            :....     ||:...||.    .......|..|.||..::...:.|              .|:.
Mouse    74 VKTYSVSYTLEDLSHHFNF----FAHKQWENREVGMFSLLKHSGKGFFQVLFSHCRSLFNDKKLV 134

  Fly   118 DVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYL---LGNPW 179
            :.:||           ..||.|.:..|..| .|.:|....:|.||....  .|..||   ...|.
Mouse   135 EYLKQ-----------RSFDAVFLDPFDVC-GLTIAKYFSLPSVVFSGG--IFCHYLDEGAQCPS 185

  Fly   180 EVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLH 244
            ..||||  .:..|....:.|..||.|....|.:|.|..........|..|:.....|:   .||.
Mouse   186 PPSYVP--RILSKFADTMTFKERVWNYFSYMKERAFCPYFFKTAIEIASEVLQTPVTM---TDLF 245

  Fly   245 KNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPER-LPQNMEQFL-SEAPNGAILLSLGSN 307
            .::|:..|.:..:.|.| ||.:|.::.||||..  .|.: |.:..|.:: :...:|.::.||||.
Mouse   246 SSVSIWMFRTDFVLEFP-RPVMPNMVYIGGINC--HPGKPLSKEFEAYVNASGEHGIVVFSLGSM 307

  Fly   308 LKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDVLAHPNITLFI 370
            :.|  :......::...|.::.|.|:|::...  .|:   ::|.:..||:||.|:|.||....||
Mouse   308 VSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKTRAFI 367

  Fly   371 THAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPK 435
            ||:|..|:.|...:|.||:.:|:||||..||..|...|.|:..::|.:..|.....::.|::|..
Mouse   368 THSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKS 432

  Fly   436 YATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVILGTI 499
            |...:...|:|::|||:.|.:..::|||||:|:.||||:: |..| :::...::|||...:|..:
Mouse   433 YKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIV 496

  Fly   500 VALCFIT--------KLLFGLVVGKLR-KNSRKAKVN 527
            :.:.||.        :..||   ||.| |.|.|:|.:
Mouse   497 LTVVFIVFKCCAYGCRKCFG---GKGRVKKSHKSKTH 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	123/464 (27%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	144/530 (27%)