Protein Alignment Ugt37B1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 583
• Identity: 151/583 - (25%)
• Similarity: 255/583 - (43%)
• Gaps: 130/583 - (22%)

  Fly    10 LQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTV----VTILKPPSLHKDINH 70
            |.::..:..|.|..:| :| .:..||.:....:.|.|..|||...|    ||:           |
  Rat    14 LLLLYALPWAEGGKVL-VF-PMEGSHWLSMRDVVRELHARGHQAVVLAPEVTV-----------H 65

  Fly    71 ILVPMEEDIL-----------QAFNSVVGGMTKTDNSNAYVSMFRSVRQLSE------TFSKMGD 118
            |   .|||..           |.|..               .|.|:::.:.|      ||.:..:
  Rat    66 I---KEEDFFTLQTYPVPYTRQGFRQ---------------QMMRNIKVVFETGNYVKTFLETSE 112

  Fly   119 VMKQ---PLVK---------DLYEH-PDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSF 170
            ::|.   .|::         .|.:| ..:.||:|:....:.| ...||..|.:|.|.       |
  Rat   113 ILKNISTVLLRSCMNLLHNGSLLQHLNSSSFDMVLTDPVIPC-GAVLAKYLGIPTVF-------F 169

  Fly   171 LGYL--------LGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIY 227
            |.|:        ...|...||:|.:...:  ...:.|..||.|:|..:|.:........|...:.
  Rat   170 LRYIPCGIDSEATQCPKPSSYIPNLLTML--SDHMTFLQRVKNMLYPLALKYICHFSFTRYESLA 232

  Fly   228 REIYGDDPTLPSYEDLHKNISLIFFASHG---------ISEGPIRPNVPAVIEIGGIQ-VKEQPE 282
            .|:            |.:.:||:...||.         :.:.| ||.:|.::.||||. |.::|
  Rat   233 SEL------------LQREVSLVEVLSHASVWLFRGDFVFDYP-RPVMPNMVFIGGINCVIKKP- 283

  Fly   283 RLPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDL--DNIPG 344
             |.|..|.:: :...:|.::.||||.:.|  :......::...|.::.|.|:|::...  .|:
  Rat   284 -LSQEFEAYVNASGEHGIVVFSLGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL-- 343

  Fly   345 ESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGF 409
             ::|.:..||:||.|:|.||....||||:|..|:.|...:|.||:.:|:||||..||..|...|.
  Rat   344 -AKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGA 407

  Fly   410 GIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHI 474
            |:..::|.:..|.....::.|::|..|...:...|:|::|||:.|.:..::|||||:|:.||||:
  Rat   408 GVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHL 472

  Fly   475 QSPVVH-MSYIAANNLDVYAVILGTIVALCFIT--------KLLFGLVVGKLR-KNSRKAKVN 527
            : |..| :::...::|||...:|..::.:.||.        :..||   ||.| |.|.|:|.:
  Rat   473 R-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFG---GKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	121/493 (25%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	143/560 (26%)