Protein Alignment Ugt37B1 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 541
• Identity: 148/541 - (27%)
• Similarity: 245/541 - (45%)
• Gaps: 78/541 - (14%)

  Fly    18 GAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLHKDINHILVPMEEDILQA 82
            |:|..||..|...               |.:|.|:|||:.    ||....||..|     |....
Mouse    31 GSHWLNIKILLEE---------------LVQRNHSVTVLA----PSETLFINSRL-----DAFIN 71

  Fly    83 FNSVVGGMTKT--------------DNSNAYVSMFRSVRQLSE-------TFSKMGD-VMKQPLV 125
            |..:....||:              |:....::|:...::|..       |..:|.| |:..|.|
Mouse    72 FEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTV 136

  Fly   126 KDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSF-----LGYLLGNPWEVSYVP 185
            .:..:  ...||:::......|.:| :|.||.:|.|..|...|:|     .|.:   |..:||||
Mouse   137 MERLQ--KGGFDVLLADPVTMCGEL-VALKLGIPFVYTLRFSPAFTVERHCGKI---PAPISYVP 195

  Fly   186 GMSVSIKGGKPLGFGHRVLNLLG-SMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISL 249
            .....:.  ..:.||.||.|::. |:...:|.......|: .|.::.|...||  .|.:.| ..:
Mouse   196 AALSELT--DQMSFGERVKNIISYSLQDYIFKTYWGEWNS-YYSKVLGRPTTL--CETMGK-AEI 254

  Fly   250 IFFASHGISEGPIRPNVPAVIEIGGIQVKEQPER-LPQNMEQFL-SEAPNGAILLSLGSNLKEDH 312
            ....::...|.| ||.:|....:||:..|  |.: ||:.||:|: :...:|.::.||||.:|  :
Mouse   255 WLMRTYWDFEFP-RPYLPNFEFVGGLHCK--PAKPLPKEMEEFVQTSGEHGIVVFSLGSMVK--N 314

  Fly   313 LKSSTVQKMFNVLSKLQQKVIWKWDDLDNIPGE-SENILYSKWVPQVDVLAHPNITLFITHAGKG 376
            |.......:.:.|:::.|||:|::.  ..||.. ..|.....|:||.|:|.||....||||.|..
Mouse   315 LTDEKANLIASALAQIPQKVLWRYK--GKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTN 377

  Fly   377 GLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVK 441
            |:.||.|||.||:.:|:|.|||.|...|...|..::.::.|:.....|..:|.|::.|.|.....
Mouse   378 GIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPSYKENAM 442

  Fly   442 SFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIV-ALCFI 505
            ..|.::.|:|:.|.:..::|:|:|:|:.||.|::.....:|:...::|||...:|..:. |:..:
Mouse   443 RLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLV 507

  Fly   506 TK-LLFGLVVGKLRKNSRKAK 525
            .| .||  :..|:.|..:|.|
Mouse   508 AKCCLF--IFQKVGKTGKKKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	146/537 (27%)
		egt	13..483	CDD:223071	135/495 (27%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	144/529 (27%)
		egt	<267..487	CDD:223071	73/225 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840216
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840