Protein Alignment Ugt37B1 and ugt1ab

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_998587.3
• Gene: ugt1ab / 406731
• ZFINID: ZDB-GENE-040426-2762
• Length: 536
• Species: Danio rerio
• Alignment Length: 577
• Identity: 147/577 - (25%)
• Similarity: 260/577 - (45%)
• Gaps: 104/577 - (18%)

  Fly     2 GGISRCLALQIVVLIAGAHGANILGLFTS------------LSPSHLVIQMSMARILAERGHNVT 54
            ||:.|.|.:..:.|.|      .|.||:|            :..||.:....:...::.|||.:.
Zfish     9 GGMKRTLFVPALGLFA------FLCLFSSESVQAGKVLVMPVDGSHWLSMKILVEEMSSRGHEMV 67

  Fly    55 VV----TILKPPSLHKDINHILVPMEEDILQAFNSVVGGMTKT--DNSNAYVSMFRSVRQLSETF 113
            |:    :||...|.:.......||...|.|   |:.|..:.||  :.:..::.:..::..|.: |
Zfish    68 VLVPETSILIGKSGNFTTKSFRVPYSFDEL---NAHVDHIRKTAIEKAPRFIDIVGALGNLIQ-F 128

  Fly   114 SKM------GDVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVAL-------- 164
            :.|      |.:..:||:|.|   .|.|||.::...|:.|..: :|....:|.|..|
Zfish   129 TNMQVKACEGLLYDEPLMKSL---RDMKFDALLTDPFLPCGSV-IADYFSIPAVYFLRGIPCRLD 189

  Fly   165 ------SNPPSFLGYLLGNPWEVSYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRN 223
                  .:||||:....     ..|...|:          |..|::|        .||.:.|
Zfish   190 EAAAQCPSPPSFIPRFF-----TGYTDKMT----------FSQRMIN--------TFMTVFE--- 228

  Fly   224 ARIYREIYGD-DPTLPSYEDLHKNISLIFFASHGI---------SEGPIRPNVPAVIEIGGIQ-V 277
            ..:..:::.. |.....|  |.|:.|......||.         .|.| :|.:|.:::||||. .
Zfish   229 KYLCHQLFASFDELATRY--LKKDTSYAELLGHGAVWLLRYDFSFEYP-KPQMPNMVQIGGINCA 290

  Fly   278 KEQPERLPQNMEQFLS-EAPNGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDD--L 339
            |..|  |.:.:|:|:: ...:|.::.:|||.:.:  |..:..::.|....::.|:|:|::..  .
Zfish   291 KRAP--LTKELEEFVNGSGEHGFVVFTLGSMVSQ--LPEAKAREFFEAFRQIPQRVLWRYTGPVP 351

  Fly   340 DNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVM 404
            :|.|   :|:...||:||.|:|.||.:..|:||.|..|:.|...:|.||:.||:||||..||..:
Zfish   352 ENAP---KNVKLMKWLPQNDLLGHPKVRAFVTHGGSHGIYEGICNGVPMVMLPLFGDQGDNAQRL 413

  Fly   405 VMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYH 469
            |..|.....:|..:..:..|..:::|:::..|...:...|.::||||:.|.:..::|.|:|:|:.
Zfish   414 VSRGVAESLTIYDVTSEKLLVALKKVINDKSYKEKMMKLSAIHRDRPIEPLDLAVFWTEFVMRHK 478

  Fly   470 GAPHIQSPVVH-MSYIAANNLDVYAVILGTIVALCFITKLLFGLVVGKLRKNSRKAK 525
            ||.|:: |..| :::|..::|||...:|..::.:.|:|.........|..|.|:|.|
Zfish   479 GAEHLR-PAAHDLNWIQYHSLDVIGFLLLILLTVIFVTVKSCMFCFRKCFKKSQKKK 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	120/490 (24%)
ugt1ab	NP_998587.3	None