Protein Alignment Ugt37B1 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 151/561 - (26%)
• Similarity: 258/561 - (45%)
• Gaps: 86/561 - (15%)

  Fly    10 LQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTV----VTI-LKP-------- 61
            |.::..:..|.|..:| :| .:..||.:....:.|.|..|||...|    ||: :|.
  Rat    14 LLLLCALPWAEGGKVL-VF-PMEGSHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFTLQT 76

  Fly    62 ---PSLHKDINHILVPMEEDILQ---AFNSVVGGMTKTDN-SNAYVSMFRSVRQLSETFSKMGDV 119
               |...::..|.|:...::..:   :...|:..|...:| |..||   ||.|         |.:
  Rat    77 YPVPYTKEEYRHHLLGHLQNFFETEFSLKLVLQRMAAVNNVSTFYV---RSCR---------GLL 129

  Fly   120 MKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGN-PWEVSY 183
            ....|::.|   ..:.||:|:...|..| ...||..|:||.|..|.:....|.:...| |...||
  Rat   130 HNTALIQSL---NSSSFDVVLTDPFFPC-GAVLAMYLRVPAVFFLQSMLCELEFEATNSPNPSSY 190

  Fly   184 VPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNIS 248
            :|.:..  .....:.|..||.|:|..:.   :|::..:.        ||....|.| :.|.:.:|
  Rat   191 IPRLLT--LNSDHMSFLDRVKNMLYPVP---WMYLCHVN--------YGSLARLAS-DLLQREVS 241

  Fly   249 LIFFASHG---------ISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFL-SEAPNGAILLS 303
            ::....|.         :...| ||.:|.::.||||....: :.|.|..|.:: :...:|.::.|
  Rat   242 VVEILRHASVWLLRKDFVFYYP-RPFMPNMVFIGGINCANR-KPLSQEFEAYVNASGEHGIVVFS 304

  Fly   304 LGSNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDVLAHPNI 366
            |||.:.|  :......::...|.::.|.|:|::...  .|:   ::|.:..||:||.|:|.||..
  Rat   305 LGSMVSE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKA 364

  Fly   367 TLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVL 431
            ..||||:|..|:.|...:|.||:.:|:||||..||..|...|.|:..::|.:..|.....::.|:
  Rat   365 RAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVI 429

  Fly   432 DNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVI 495
            :|..|...:...|:|::|||:.|.:..::|||||:|:.||||:: |..| :::...::|||...:
  Rat   430 NNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFL 493

  Fly   496 LGTIVALCFIT--------KLLFGLVVGKLR-KNSRKAKVN 527
            |..::.:.||.        :..||   ||.| |.|.|:|.:
  Rat   494 LAIVLTVVFIVYKSCAYGCRKCFG---GKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	121/471 (26%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	143/538 (27%)