Protein Alignment Ugt37B1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 555
• Identity: 151/555 - (27%)
• Similarity: 269/555 - (48%)
• Gaps: 59/555 - (10%)

  Fly     5 SRCLALQIVVLI-----AGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSL 64
            ||.|.|...:|:     :.:|...:| :| .:..||.:..:.:.:.|.::||.  ||.|....|:
Mouse     8 SRLLLLLPYLLLCVFGPSASHAGRLL-VF-PMDGSHWLSMLGVIQQLQQKGHE--VVVIAPEASI 68

  Fly    65 H-KD-----INHILVPMEEDILQAFNSVVGGMTKTDNS------NAYVSMFRSVRQLSETFSKMG 117
            | |:     :....||.:::.:.|....:|......:|      ..|:.:.|....|....|.:
Mouse    69 HIKEGSFYTLRKFPVPFQKENVTATLVELGRTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHL- 132

  Fly   118 DVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFL-GYLLGNPWEV 181
             :.....:..|.|   :.||.::...|:.|..: :|..|.||.|..|:..|..| ......|..:
Mouse   133 -LHNAEFMASLEE---SHFDALLTDPFLPCGSI-VAQYLTVPTVYFLNKLPCSLDSEATQCPVPL 192

  Fly   182 SYVPGMSVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKN 246
            |||| .|:|....: :.|..||.|:|.::::.....::......:..||...:.|:   :||...
Mouse   193 SYVP-KSLSFNSDR-MNFLQRVKNVLLAVSENFMCRVVYSPYGSLATEILQKEVTV---QDLLSP 252

  Fly   247 ISLIFFASHGISEGPIRPNVPAVIEIGGIQ-VKEQPERLPQNMEQFL-SEAPNGAILLSLGSNLK 309
            .|:....|..:.:.| ||.:|.::.||||. ::::|  |.|..|.:: :...:|.::.||||.:.
Mouse   253 ASIWLMRSDFVKDYP-RPIMPNMVFIGGINCLQKKP--LSQEFEAYVNASGEHGIVVFSLGSMVS 314

  Fly   310 EDHLKSSTVQKMFNVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDVLAHPNITLFITH 372
            |  :......::...|.::.|.|:|::...  .|:   ::|.:..||:||.|:|.||....||||
Mouse   315 E--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKTRAFITH 374

  Fly   373 AGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYA 437
            :|..|:.|...:|.||:.:|:||||..||..|...|.|:..::|.:..|.....::.|::|..|.
Mouse   375 SGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYK 439

  Fly   438 TAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVILGTIVA 501
            ..:...|:|::|||:.|.:..::|||||:|:.||||:: |..| :::...::|||...:|..::.
Mouse   440 ENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLT 503

  Fly   502 LCFIT--------KLLFGLVVGKLR-KNSRKAKVN 527
            :.||.        :..||   ||.| |.|.|:|.:
Mouse   504 VVFIVFKCCAYGCRKCFG---GKGRVKKSHKSKTH 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	118/455 (26%)
Ugt1a1	NP_964007.2	UDPGT	30..526	CDD:278624	140/522 (27%)