Protein Alignment Ugt37B1 and Ugt1a6b

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 542
• Identity: 158/542 - (29%)
• Similarity: 261/542 - (48%)
• Gaps: 68/542 - (12%)

  Fly    22 ANILG---LFTSLSPSHLVIQMSMARILAERGHNVTV----VTILKPPSLHKDINHILVPME-ED 78
            |::||   |......||.:....:...|:||||::.|    |.:|...|.:.......||.. |:
Mouse    22 ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKIFSVPYSLEE 86

  Fly    79 ILQAFNS-----------VVGGMTKTDNSNAYVSMFRSVRQLSETFSKMGDVMKQPLVKD---LY 129
            :...|.:           ::|.:.:..||...:.||         ||..     |.|:||   |.
Mouse    87 LQTRFRTFGRNQFVPGAPLMGPLREYRNSMLTLEMF---------FSNC-----QSLLKDSATLS 137

  Fly   130 EHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLG-NPWEVSYVPGMSVSIKG 193
            ...:||||.:.....|.| .:.||..|.:|.|......|..|.::|| :|..|||||....  |.
Mouse   138 FLRENKFDALFTDPAMPC-GVILAEYLNLPSVYLFRGFPCSLEHMLGQSPSPVSYVPRFYT--KF 199

  Fly   194 GKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFFASHGIS 258
            ...:.|..|:.|.:.::.:....:.:..:...|..::...|.:|||   ||:| ||.......:.
Mouse   200 SDHMTFPQRLANFIVNILENYLYYCLYSKYEIIVTDLLKRDVSLPS---LHQN-SLWLLRYDFVF 260

  Fly   259 EGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQKMF 322
            |.| ||.:|.:|.||||..|:: .:|.|..|.:: :...:|.::.||||.:.|  :......::.
Mouse   261 EYP-RPIMPNMIFIGGINCKKK-GKLTQEFEAYVNASGEHGIVVFSLGSMVSE--IPEKKAMEIA 321

  Fly   323 NVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHG 385
            ..|.::.|.|:|::...  .|:   ::|.:..||:||.|:|.||....||||:|..|:.|...:|
Mouse   322 EALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNG 383

  Fly   386 KPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDR 450
            .||:.:|:||||..||..|...|.|:..::|.:..|.....::.|::|..|...:...|:|::||
Mouse   384 VPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDR 448

  Fly   451 PLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVILGTIVALCFIT-------- 506
            |:.|.:..::|||||:|:.||||:: |..| :::...::|||...:|..::.:.||.
Mouse   449 PIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCAYGC 512

  Fly   507 KLLFGLVVGKLR-KNSRKAKVN 527
            :..||   ||.| |.|.|:|.:
Mouse   513 RKCFG---GKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	131/464 (28%)
Ugt1a6b	NP_958812.3	UDPGT	27..522	CDD:278624	150/526 (29%)