Protein Alignment Ugt37B1 and Ugt1a10

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_964003.2
• Gene: Ugt1a10 / 394430
• MGIID: 3580642
• Length: 530
• Species: Mus musculus
• Alignment Length: 548
• Identity: 154/548 - (28%)
• Similarity: 247/548 - (45%)
• Gaps: 57/548 - (10%)

  Fly     7 CLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILKPPSLHKDIN-- 69
            |:.|   :|.:|...|..| |...:..||......:...|.:|||.|.||.......|.|.:|
Mouse    13 CVCL---LLASGLVQAGRL-LVVPMDGSHWFDMQMVVEKLIQRGHEVVVVIPEVSWRLGKSLNCT 73

  Fly    70 -------HILVPMEEDILQAFNSVVGGMTKTDNSNAYVSMFRSVRQLSE-TFSKMGDVMKQPLVK 126
                   |.|    ||:.:.|........||...:....|..|.|...| .||....:...   |
Mouse    74 VKTYSVSHTL----EDLDREFKYFTYTQWKTPEQSIRSFMTGSARGFFELMFSHSRGLFND---K 131

  Fly   127 DLYEH-PDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFLGYLLGN---PWEVSYVPGM 187
            .|.|: ....||.|.:..|..| .|.:|..|.:|.|:...  .||..||...   |..:||||
Mouse   132 KLVEYLKQRSFDAVFLDPFDVC-GLIVAKYLSLPSVIFAR--LSFCYYLEEGAQCPSLLSYVP-- 191

  Fly   188 SVSIKGGKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDLHKNISLIFF 252
            .:..|....:.|..||.|....:...:|..........|..|:.....|:   .||...:|:...
Mouse   192 RLFSKYTDTMTFKERVWNHYMYIEDYVFCPYFFKTAVEIASEVLQTPVTM---TDLFSPVSIWLL 253

  Fly   253 ASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSS 316
            .:..:.|.| ||.:|.::.:||:... |.:.|.:..|.:: :...:|.::.||||.:.|  :...
Mouse   254 RTDFVLEFP-RPVMPNMVFVGGMNCL-QGKPLSKEFEAYVNASGEHGIVVFSLGSMVSE--IPEK 314

  Fly   317 TVQKMFNVLSKLQQKVIWKWDDL--DNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLT 379
            ...::...|.::.|.|:|::...  .|:   ::|.:..||:||.|:|.||....||||:|..|:.
Mouse   315 KAMEIAEALGRIPQTVLWRYTGTRPSNL---AKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIY 376

  Fly   380 EAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFS 444
            |...:|.||:.:|:||||..||..|...|.|:..::|.:..|.....::.|::|..|...:...|
Mouse   377 EGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLS 441

  Fly   445 TLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANNLDVYAVILGTIVALCFIT-- 506
            :|::|||:.|.:..::|||||:|:.||||:: |..| :::...::|||...:|..::.:.||.
Mouse   442 SLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFK 505

  Fly   507 ------KLLFGLVVGKLR-KNSRKAKVN 527
                  :..||   ||.| |.|.|:|.:
Mouse   506 CCAYGCRKCFG---GKGRVKKSHKSKTH 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	123/455 (27%)
Ugt1a10	NP_964003.2	UDPGT	26..521	CDD:278624	144/521 (28%)