DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37B1 and Ugt36E1

DIOPT Version :9

Sequence 1:	NP_525008.2	Gene:	Ugt37B1 / 53584	FlyBaseID:	FBgn0026755	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_609911.1	Gene:	Ugt36E1 / 35139	FlyBaseID:	FBgn0027070	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	552	Identity:	171/552 - (30%)
Similarity:	282/552 - (51%)	Gaps:	66/552 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 CLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILK---PPSLHKDI 68
            || |.::.|:|.:....|||||...:.||......:.|.|||.||:|.|::..:   ||:.:||
  Fly     9 CL-LALLSLVAFSDSLRILGLFPHPAISHFKFFHPIMRGLAEAGHSVDVISPFEDKDPPNGYKD- 71

  Fly    69 NHILVPMEEDILQAFNSVVGGMTKTDNSNAYVSMFRSVRQLSETF--SKMG-----DVMKQPLVK 126
             |:|.|         :::...::..|....|..:|..|    |.|  .|||     ..:....:.
  Fly    72 -HLLPP---------STLTDTISLEDFERPYSFLFHYV----EFFILHKMGREDCNTTLHSRALT 122

  Fly   127 DLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSN----PPSFLGYLLGNPWEVSYVPGM 187
            ::.::|...:|::::..|.....:::||..:.| |:.:|:    |..:..:  |.|...||:
  Fly   123 EILKNPPGYYDVILLEQFNTDCAMSVAHVFQAP-VIGMSSCALMPWHYERF--GAPLIPSYI--- 181

  Fly   188 SVSIKG-GKPLGFGHRV--------LNLLGSMAQRLFMFIIELRNARIYREIYGDDPTLPSYEDL 243
            |...:| .:.:.|..|:        ||||..      ||.:...||.| |:.:|  |.|||.|||
  Fly   182 SALFQGQSQEMSFAGRLGNWITVHSLNLLYK------MFTVPAGNALI-RQRFG--PGLPSTEDL 237

  Fly   244 HKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPERLPQNMEQFLSEAPNGAILLSLGSNL 308
            .:|.||:....|....|| :|..|.|||:||:.: ..|:.||.::::.|..||.|.||:|.||.|
  Fly   238 VRNTSLMLVNQHFSLSGP-KPLPPNVIEVGGVHI-SPPKPLPSDLQKILDNAPKGVILISWGSQL 300

  Fly   309 KEDHLKSSTVQKMFNVLSKLQQKVIWKWDDLDNIPGESENILYSKWVPQVDVLAHPNITLFITHA 373
            |...|.::....:...:.:|:|:||||::: |.:|.:..|:...||:||.|:|||||:.:|::|.
  Fly   301 KACSLSAARRDGIVKAIGRLEQEVIWKYEN-DTLPNKPPNLHIRKWLPQRDILAHPNLKVFMSHG 364

  Fly   374 GKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFLQGIREVLDNPKYAT 438
            |..|.|||.....|::.:|::|||..|...:|..|..::..:..|:|::..:.:.:.|| |.:..
  Fly   365 GLMGTTEAVSSAVPIVGVPIYGDQSLNIAALVQRGMALQLELKKLDENTVYEALTKALD-PSFKA 428

  Fly   439 AVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVHMSYIAANNLDVYAVILGTIVALC 503
            ..|..::.|.:|...|.||.|:|||:|....|||..|...||:|.....:||||:|     |||.
  Fly   429 RAKEVASSYNNRIQGPLETAIWWVEHVAETKGAPLTQPSAVHLSRFVYYSLDVYSV-----VALS 488

  Fly   504 FITKLLFGLVVGKLRKNSRKAKVNQKHKLKKK 535
            .:..::  .::|.:|...|:.....: |||:|
  Fly   489 LLLPVI--TLLGLIRMFKRREPKGDR-KLKRK 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	163/533 (31%)
Ugt37B1	NP_525008.2	egt	13..483	CDD:223071	152/492 (31%)
Ugt36E1	NP_609911.1	egt	3..460	CDD:223071	149/485 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454634
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	7	6.940