Protein Alignment Ugt37B1 and Ugt2b15

DIOPT Version :10

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_695226.3
• Gene: Ugt2b15 / 266685
• RGDID: 628623
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 163/574 - (28%)
• Similarity: 264/574 - (45%)
• Gaps: 111/574 - (19%)

  Fly     4 ISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAE---RGHNVTVVTILKPPSLH 65
            ||..|.|||.......:...:|     :.|......|::..||.|   |||.|||   |||.:.
  Rat     6 ISALLLLQISCCFQSGNCGKVL-----VWPMEFSHWMNIKTILDELVQRGHEVTV---LKPSAY- 61

  Fly    66 KDINHILVPMEEDILQAFNSVVGGMTKTDNSNAYVSM-----FRSVRQLSETFSKM--------- 116
                ::|.|.:...|: |.:....::|.:..|.::.:     :...|....::|.:
  Rat    62 ----YVLDPKKSPDLK-FETFPTSVSKDELENYFIKLVDVWTYELQRDTCLSYSPLLQNMIDGFS 121

  Fly   117 --------GDVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSF--- 170
                    ..|..:.|:..|.|   :|||:::......|.:| :|..|.:|.:.:|...|.:
  Rat   122 DYYLSLCKDTVSNKQLMAKLQE---SKFDVLLSDPVAACGEL-IAEVLHIPFLYSLRFSPGYKIE 182

  Fly   171 --LGYLLGNPWEVSYVPGMSVSIKG-GKPLGFGHRVLNLLGSMAQRLFMFIIELRNAR----IYR 228
              .|..:..|   ||||   |.:.| |.|:.|..||.|::.::   .|.|...:.||:    .|.
  Rat   183 KSSGRFILPP---SYVP---VILSGMGGPMTFIDRVKNMICTL---YFDFWFHMFNAKKWDPFYS 238

  Fly   229 EIYGDDPTLP------------SYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQP 281
            ||.|...||.            ||.||               |.| .|.:|.|..|||:|.: .|
  Rat   239 EILGRPTTLAETMGKAEMWLIRSYWDL---------------EFP-HPTLPNVDYIGGLQCR-PP 286

  Fly   282 ERLPQNMEQFL-SEAPNGAILLSLGSNLKEDHLKSSTVQKMFN----VLSKLQQKVIWKWDDLDN 341
            :.||::||.|: |...:|.::.||||      :.||..::..|    .|:::.|||:||:|  ..
  Rat   287 KPLPKDMEDFVQSSGEHGVVVFSLGS------MVSSMTEEKANAIAWALAQIPQKVLWKFD--GK 343

  Fly   342 IPGE-SENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMV 405
            .|.. ..|....||:||.|:|.||....|:||.|..|:.||.|||.||:.:|:||:|..|...||
  Rat   344 TPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVYEAIYHGIPMVGIPMFGEQHDNIAHMV 408

  Fly   406 MHGFGIKQSILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHG 470
            ..|..:..:|.|:.:......::|:::||.|.......||::.|:|:.|.:..::|:|:|:|:.|
  Rat   409 AKGAAVTLNIRTMSKSDLFNALKEIINNPFYKKNAVWLSTIHHDQPMKPLDKAVFWIEFVMRHKG 473

  Fly   471 APHIQSPVVH-MSYIAANNLDVYAVIL--GTIVALCFITKLLF--GLVVGKLRK 519
            |.|:: |:.| :.:...::|||...:|  ..::|:..:...||  .|.|.|.:|
  Rat   474 AKHLR-PLGHNLPWYQYHSLDVIGFLLTCSAVIAVLTVKSFLFIYRLFVKKEKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	GT1_Gtf-like	22..461	CDD:340817	137/491 (28%)
Ugt2b15	NP_695226.3	UDPGT	24..527	CDD:278624	157/556 (28%)