Protein Alignment Ugt37B1 and Ugt2b35

DIOPT Version :9

• Sequence 1: NP_525008.2
• Gene: Ugt37B1 / 53584
• FlyBaseID: FBgn0026755
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_766469.1
• Gene: Ugt2b35 / 243085
• MGIID: 3576100
• Length: 529
• Species: Mus musculus
• Alignment Length: 558
• Identity: 161/558 - (28%)
• Similarity: 256/558 - (45%)
• Gaps: 76/558 - (13%)

  Fly     4 ISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVV----TILKPPSL 64
            ||..|.||:...........:  |...|..||.:....:...|.:|||.|||:    :|...|..
Mouse     6 ISALLLLQMSCCFRSTSCGKV--LVWPLEFSHWMNLKIILDELVQRGHEVTVLRPSASIFVDPKY 68

  Fly    65 HKDINHILVP--MEEDILQAFNSVVGGMTK----------TDNSNAY---VSMFRSVRQLSETFS 114
            ...:.....|  ..:|.|:.|      :||          .|...:|   .::|..:...|.:..
Mouse    69 SPGLKFETFPTAFSKDYLETF------LTKLVDEWTFEVPRDTCLSYSLLQTLFGKLSDYSLSLC 127

  Fly   115 KMGDVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPSFL------GY 173
            |.....||.:.|    ..::|||::::....:|.:| :|..|::|.:.:|...|.:.      |:
Mouse   128 KEAVSNKQLMTK----FQESKFDVLILDAMASCGEL-IAQLLQIPFLYSLRFSPGYQVEKNSGGF 187

  Fly   174 LLGNPWEVSYVPGMSVSIKG-GKPLGFGHRVLNLLGSMAQRLFMF--IIELRNARIYREIYGDDP 235
            :|    ..||||   |.:.| |..:.|..||.|:: .|....|.|  ..|....:.|.|..|...
Mouse   188 VL----PPSYVP---VILSGLGGQMTFTERVKNMI-CMLYFDFWFQTFTEKEWDQFYSETLGRPT 244

  Fly   236 TLPSYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQPER-LPQNMEQFL-SEAPNG 298
            ||  .|.:.| ..:.|..|:...|.| .|.:|.|..:||:..|  |.: ||:.||.|: |...:|
Mouse   245 TL--IETMGK-AEMWFIRSYWDLEFP-HPTLPNVEYVGGLHCK--PAKPLPKEMEDFVQSSGVHG 303

  Fly   299 AILLSLG---SNLKEDHLKSSTVQKMFNVLSKLQQKVIWKWDDLDNIPGE-SENILYSKWVPQVD 359
            .::.|||   ||:.|:...:.:.     .|:::.|||:|::|  ...|.. ..|....||:||.|
Mouse   304 VVVFSLGSMVSNMTEERANAISW-----ALAQIPQKVLWRFD--GKTPASLGPNTRIYKWLPQND 361

  Fly   360 VLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQSILTLEEDSFL 424
            :|.||....|:||.|..||.||.:||.||:.:|:|.:|..|...||..|..:..:|.|:.....|
Mouse   362 LLGHPKTKAFVTHGGANGLYEAIHHGIPMIGIPLFSEQHDNIAHMVAKGTAVALNIRTMSRSDLL 426

  Fly   425 QGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYHGAPHIQSPVVH-MSYIAANN 488
            ..:.||::||.|...|...||::.|:|:.|....|:|:|:|:|:.||.|:: |:.| :::...::
Mouse   427 NALEEVINNPSYKENVMWLSTIHHDQPMKPLNRTIFWIEFVMRHKGAKHLR-PLAHNLTWYQYHS 490

  Fly   489 LDVYAVILGTIVAL------CFITKLLFGLVVGKLRKN 520
            |||...:|..:||.      |.:....|.:...|.|||
Mouse   491 LDVIGFLLVCVVATAVLPVKCCLFVYQFFVKKAKKRKN 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37B1	NP_525008.2	UDPGT	12..523	CDD:278624	156/550 (28%)
		egt	13..483	CDD:223071	144/504 (29%)
Ugt2b35	NP_766469.1	egt	8..506	CDD:223071	153/532 (29%)
		UDPGT	24..525	CDD:278624	152/535 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840